메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색
질문

논문 기본 정보

자료유형
학술저널
저자정보
저널정보
한국영양학회 Nutritional Sciences Nutritional Sciences Vol.9 No.1
발행연도
2006.2
수록면
29 - 34 (6page)

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색
질문

초록· 키워드

오류제보하기
Purified rat liver aryl sulfotransferase Ⅳ (AST Ⅳ) was found to be inhibited in vitro by zinc, copper, cadmium and terbium, Among these four elements, zinc, copper and cadmium were all strongly inhibitory to the AST Ⅳ activity at very low concentratiom (2.5 ㎛ to 0.025 ㎛). In rat liver cytosol, zinc, copper and cadmium at 25 ㎛ to 0.025 ㎛ also decreased the AST Ⅳ activity to 50% of the controls. In order to assess the possible effects of these metals on the AST Ⅳ activity recovery pattern in vivo, studies on the relationship between these minerals and dietary 2-acetylaminofluorene were conducted Total of forty rats were fed one of five diets for 6 weeks: diet 1, Control diet phis 2-acetlyaminofluorene (0.05%); diet 2, zinc-deficient diet plus 2-acetlyaminofluorene; diet 3, zinc-supplement diet plus 2-acetylaminofluorene; diet 4, copper-supplement diet plus 2-acetiyaminofluorene; diet 5, cadmium-supplement diet plus 2-acetylaminofluorene. Half of the rats from each diet were changed to individual diet after 3 weeks of 2-acetylamnofluorene feeding. Placement of rats on the control diet following one cycle of 2-acetylaminofluorene feeding of 3 weeks without 2-acetylaminofluorene resulted in nearly full recovery of AST Ⅳ activity within 3 or 4 weeks. However, the rats fed diets that supplemented with zinc, copper or cadmium without 2-acetylaminofluorene showed a new pattern of lowered AST Ⅳ activity as early as the first cycle. Also, lowering in cytosolic AST Ⅳ contents was appeared in the Iivers from the rats, following one cycle of 2-acetlyaminofluorene feeding of 3 weeks, fed one of the diets that supplemented with copper, cadmium or zinc without 2-acetylaminofluorene for ensuing 3 weeks.

목차

INTRODUCTION
MATERIALS AND METHODS
REESULTS
DISCUSSION
Literature cited

참고문헌 (0)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0

UCI(KEPA) : I410-ECN-0101-2012-594-004194705