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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Journal of Food Science and Nutrition Journal of Food Science and Nutrition Vol.16 No.3
- 발행연도
- 2011.9
- 수록면
- 224 - 229 (6page)
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초록· 키워드
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The radical scavenging activity and inhibition effect from lipid peroxidation induced by peroxyl radical of methanol extract from Perilla frutescens and its active compound, rosmarinic acid (RA), were investigated in vitro.
The treatment of extract and RA scavenged 1,1-diphenyl-2-picrylhydrazyl, hydroxyl radical (·OH) and nitric oxide in a concentration-dependent manner. In particular, the extract and RA showed strong radical scavenging activity against ·OH, the most toxic and reactive radical. In addition, Perilla frutescens and RA effectively inhibited lipid oxidation induced by sodium nitroprusside and 2, 2'-azobis(2-aminopropane) dihydrochloride, determined by the ferric thiocyanate method. The present results suggest that Perilla frutescens and RA play a protective role against oxidative stress induced by free radical and lipid peroxidation.
The treatment of extract and RA scavenged 1,1-diphenyl-2-picrylhydrazyl, hydroxyl radical (·OH) and nitric oxide in a concentration-dependent manner. In particular, the extract and RA showed strong radical scavenging activity against ·OH, the most toxic and reactive radical. In addition, Perilla frutescens and RA effectively inhibited lipid oxidation induced by sodium nitroprusside and 2, 2'-azobis(2-aminopropane) dihydrochloride, determined by the ferric thiocyanate method. The present results suggest that Perilla frutescens and RA play a protective role against oxidative stress induced by free radical and lipid peroxidation.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
ACKNOWLEDGEMENTS
REFERENCES
참고문헌 (33)
참고문헌 신청
1. [학술지(정기간행물)] - Turner TT / 2008 / Oxidative stress: a common factor in testicular dysfunction / J Androl 29 : 488 ~ 498
2. [학술지(정기간행물)] - Piao XS / 2008 / Antioxidative activity of geranium (Pelargonium inquinans Ait) and its active component, 1,2,3,4,6-penta-o-galloyl-beta-D-glucose / Phytother Res 22 : 534 ~ 538
3. [학술지(정기간행물)] - Halliwell B / 1987 / Oxidants and human disease: some new concepts / FASEB J 1 : 358 ~ 364
4. [학술지(정기간행물)] - Slater TF / 1984 / Free-radical mechanisms in tissue injury / Biochem J 222 : 1 ~ 15
5. [학술지(정기간행물)] - Makino T / 2003 / Anti-allergic effect of Perilla frutescens and its active constituents / Phytother Res 17 : 240 ~ 243
2. [학술지(정기간행물)] - Piao XS / 2008 / Antioxidative activity of geranium (Pelargonium inquinans Ait) and its active component, 1,2,3,4,6-penta-o-galloyl-beta-D-glucose / Phytother Res 22 : 534 ~ 538
3. [학술지(정기간행물)] - Halliwell B / 1987 / Oxidants and human disease: some new concepts / FASEB J 1 : 358 ~ 364
4. [학술지(정기간행물)] - Slater TF / 1984 / Free-radical mechanisms in tissue injury / Biochem J 222 : 1 ~ 15
5. [학술지(정기간행물)] - Makino T / 2003 / Anti-allergic effect of Perilla frutescens and its active constituents / Phytother Res 17 : 240 ~ 243
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