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논문 기본 정보

자료유형
학술저널
저자정보
Jong-Ryul Choi (Kyung Hee University) Sung-Woon Hong (Kyung Hee University) Yuri Kim (Kyung Hee University) Se-Eun Jang (Kyung Hee University) Nam-Jae Kim (Kyung Hee University) Myung Joo Han (Kyung Hee University) Dong-Hyun Kim (Kyung Hee University)
저널정보
고려인삼학회 Journal of Ginseng Research Journal of Ginseng Research Vol.35 No.3
발행연도
2011.9
수록면
301 - 307 (7page)

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초록· 키워드

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To evaluate the difference in expressing pharmacological effects of ginseng by intestinal microflora between Koreans, metabolic activities of ginseng, ginsenoside Rb<sub>1</sub> and Rg<sub>1</sub> by 100 fecal specimens were measured. The β-glucosidase activity for p-nitrophenyl-β-D-glucopyranoside was 0 to 0.42 μmol/min/mg and its average activity (mean±SD) was 0.10±0.07 μmol/min/mg. The metabolic activities of ginsenosides Rb<sub>1</sub> and Rg<sub>1</sub> were 0.01 to 0.42 and 0.01 to 0.38 pmol/min/mg, respectively. Their average activities were 0.25±0.08 and 0.15±0.09 pmol/min/mg, respectively. The compound K-forming activities from ginsenoside Rb<sub>1</sub> and ginseng extract were 0 to 0.11 and 0 to 0.02 pmol/min/mg, respectively. Their average compound K-forming activities were 0.24±0.09 pmol/min/mg and 2.14±3.66 fmol/min/mg, respectively. These activities all were not different between males and females, or between ages. Although compound K-forming activity from the aqueous extract of ginseng was low compared to that from ginenoside Rb<sub>1</sub>, their profiles were similar to those of isolated compounds. Based on these findings, we believe that the intestinal bacterial metabolic activities of ginseng components are variable in individuals and may be used as selection markers for responders to ginseng.

목차

INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
ACKNOWLEDGEMENTS
REFERENCES

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