지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.12
- 수록면
- 1,357 - 1,360 (4page)
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초록· 키워드
오류제보하기
Propionibacterium acnes is the predominant organism in sebaceous regions of the skin and is thought to play an important role in the pathogenesis of inflamed lesions. Antibacterial compounds against P. acnes were isolated from the ethanol extract of Kaempferia pandurata Roxb. and identified as panduratin A and isopanduratin A. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of panduratin A for P. acnes were 2 and 4 ㎍/㎖, respectively, while those of isopanduratin A were 4 and 8 ㎍/㎖, respectively. The time-dependent killing effect showed that panduratin A and isopanduratin A completely inhibited the growth of P. acnes at 4 and 8 ㎍/㎖ in 48 hr, respectively. Panduratin A and isopanduratin A demonstrated high antibacterial activities not only against P. acnes but also other skin microorganisms. The results suggest that panduratin A and isopanduratin A could be employed as natural antibacterial agents to inhibit the growth of acne and skin disease causing microorganisms.
목차
Abstract
Introduction
Materials and Methods
Results and Discussion
Acknowledgments
References
참고문헌 (17)
참고문헌 신청
Marples RR / 1974 / The microflora of the face and acne lesions / J. Invest. Dermatol 62:326~331
Downing DT / 1986 / Essential fatty acids and acne / J. Am. Acad. Dermatol 14:221~225
Worret WI / 2006 / Acne therapy with topical benzoyl peroxide, antibiotics, and azelaic acid / J. Dtsch. Dermatol. Ges 4:293~300
Lim YS / 1995 / A study on the MIC of antibiotics for Propionibacterium acnes in patients with acne / Korean J. Dermatol 33:437~444
Kyung-Min Park / 2005 / Antibacterial Activity of Panduratin A Isolated from Kaempferia pandurata against Porphyromonas gingivalis / Food Science and Biotechnology 14(2):286~289
Downing DT / 1986 / Essential fatty acids and acne / J. Am. Acad. Dermatol 14:221~225
Worret WI / 2006 / Acne therapy with topical benzoyl peroxide, antibiotics, and azelaic acid / J. Dtsch. Dermatol. Ges 4:293~300
Lim YS / 1995 / A study on the MIC of antibiotics for Propionibacterium acnes in patients with acne / Korean J. Dermatol 33:437~444
Kyung-Min Park / 2005 / Antibacterial Activity of Panduratin A Isolated from Kaempferia pandurata against Porphyromonas gingivalis / Food Science and Biotechnology 14(2):286~289
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UCI(KEPA) : I410-ECN-0101-2013-573-000858630