Cellulose Electro-Active Paper (EAPap) is attractive as a bio-mimetic actuator due to its merits in terms of lightweight, dry condition, large displacement output, low actuation voltage and low power consumption. Cellulose has been regenerated so as to align its microfibrils along a direction, which results in a piezoelectric paper. By chemically bonding and mixing with carbon nanotubes, titanium oxide, zinc oxide, tin oxides, the cellulose EAP can be a hybrid nanocomposite that have versatile properties and can meet material requirements for many application devices. This paper introduces recent research trend of the cellulose EAPap, mainly material preparations as well as application devices including temperature and humidity sensors, biosensors, chemical sensors, flexible transistors and actuators. This paper also explains wirelessly driving technology for the cellulose EAPap, which is attractive for biomimetic robotics, surveillance and micro-aerial vehicles.