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자료유형
학술저널
저자정보
Hae Suk Cheong (Konkuk University School of Medicine) Ki-Tae Kwon (Daegu Fatima Hospital) Ji-Young Rhee (Dankook University Hospital) Seong Yeol Ryu (Keimyung University School of Medicine) Dong Sik Jung (Dong-A University School of Medicine) Sang Taek Heo (Gyeongsang National University Hospital) Sang Yop Shin (Cheju National University) Doo Ryun Chung (Sungkyunkwan University School of Medicine) Kyong Ran Peck (Sungkyunkwan University School of Medicine) Jae-Hoon Song (Asian-Pacific Research Foundation for Infectious Diseases (ARFID))
저널정보
대한기생충학열대의학회 Parasites, Hosts and Diseases The Korean Journal of Parasitology Vol.47 No.3
발행연도
2009.9
수록면
299 - 302 (4page)

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The incidence of imported malaria has been increasing in Korea. We reviewed data retrospectively to evaluate the epidemiology, clinical features, and outcomes of imported malaria from 1995 to 2007 in a university hospital. All patients diagnosed with imported malaria were included. Imported malaria was defined as a positive smear for malaria that was acquired in a foreign country. A total of 49 patients (mean age, 35.7 year; M : F = 38 : 11) were enrolled. The predominant malarial species was Plasmodium falciparum (73.5%), and the most frequent area of acquisition was Africa (55.1%), followed by Southeast Asia (22.4%) and South Asia (18.4%). Fourteen-patients (30.6%) suffered from severe malaria caused by P. falciparum and 1 patient (2.0%) died of multiorgan failure. Most of the patients were treated with mefloquine (79.2%) or quinine (10.2%); other antimalarial agents had to be given in 13.2% treated with mefloquine and 44.4% with quinine due to adverse drug events (ADEs). P. falciparum was the most common cause of imported malaria, with the majority of cases acquired from Africa, and a significant number of patients had severe malaria. Alternative antimalarial agents with lower rates of ADEs might be considered for effective treatment instead of mefloquine and quinine.

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