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논문 기본 정보

자료유형
학술저널
저자정보
박재성 (존스홉킨스 의과대학)
저널정보
한국체육과학회 한국체육과학회지 한국체육과학회지 제22권 제4호 (자연과학 편)
발행연도
2013.8
수록면
983 - 994 (12page)

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초록· 키워드

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The impact of exercise on axon regeneration processes has not been confirmed and the mechanisms underlying the benefit of exercise have not been determined in median nerve injured mouse model. The purpose of this study was to determined the effects of treadmill exercise on nerve regeneration in median nerve cut and sutured peripheral nerve regeneration mouse model in morphological and functional study methods. The exercise results were compared with that of the control and sedentary no exercised animals.
The results of this study were summarized as follows.
(1) Treadmill exercise increased the number of axon in the median nerve after PNI(Peripheral Nerve Injury)
(2) Treadmill exercise induce the proper g-ratio and myelin thickness compare with sedentary no exercised group. This means exercise inhibits morphological recovery in the median nerv after PNI.
(3) Treadmill exercise induces recovery of EMG results(CAMP and time delay(latency)) in the median nerve rather than sedentary no exercised group.
(4) Treadmill exercise induces recovery of functional behavior (grip strength and wire grid holding) test results rather than sedentary no exercised group.
These result means treadmill exercise profitable for induce the neuronal regeneration in the injured median nerve. The results of this study suggest that treadmill exercise induce the nerve regeneration in the injured median nerve and this effects were may offer a potential therapeutic adjunct to current nerve regeneration therapies in the future.

목차

Abstract
Ⅰ. 서론
Ⅱ. 연구방법
Ⅲ. 결과 및 논의
Ⅳ. 결론
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UCI(KEPA) : I410-ECN-0101-2014-690-002398055