지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Preventive Nutrition and Food Science Preventive Nutrition and Food Science Vol.18 No.4
- 발행연도
- 2013.12
- 수록면
- 227 - 233 (7page)
이용수
초록· 키워드
오류제보하기
This study investigated the protective effect of the butanol (BuOH) fraction from fermented Laminaria japonica extract (BFLJ) on AAPH-induced oxidative stress in porcine kidney epithelial cells (LLC-PK1 cells). L. japonica was fermented by Aspergillus oryzae at 35±1°C for 72 h. Freeze-dried fermented L. japonica was extracted with distilled water, and the extracted solution was mixed with ethanol and then centrifuged. The supernatant was subjected to sequential fractionation with various solvents. The BuOH fraction was used in this study because it possessed the strongest antioxidant activity among the various solvent fractions. The BuOH fraction of fermented L. japonica had a protective effect against the AAPH-induced LLC-PK1 cells damage and increased cell viability while reducing lipid peroxidation formation and increased activities of antioxidant enzymes such as superoxide dismutase and glutathione peroxidase. The inhibitory effect of BFLJ on lipid peroxidation formation had a higher value of 0.11±0.01 nmol MDA at 100 μg/mL concentration in comparison with intact BuOH fraction showing 0.22±0.08 nmol MDA at the same concentration. Furthermore, BFLJ treatment increased glutathione concentration. GSH concentration in the cell treated with BFLJ of 100 μg/mL was 1.80 pmol/L×10<SUP>5</SUP> cells. These results indicate that BFLJ protects the LLC-PK1 cells against AAPH-induced cell damage by inhibiting lipid peroxidation formation and increasing antioxidant enzyme activities and glutathione concentration.
목차
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
REFERENCES
참고문헌 (42)
참고문헌 신청
1. [학술지(정기간행물)] - Yan X / 1998 / Antioxidative activities in some common seaweeds / Plant Foods Hum Nutr 52 : 253 ~ 262
2. [단행본] - Percival E / 1967 / Chemistry and enzymology of marine algal polysaccharides / Academic Press : 157 ~ 175
3. [학술지(정기간행물)] - Ruperez P / 2002 / Potential antioxidant capacity of sulfated polysaccharides from the edible marine brown seaweed Fucus vesiculosus / J Agric Food Chem 50 : 840 ~ 845
4. [학술지(정기간행물)] - Chandini SK / 2008 / In vitro antioxidant activities of three selected brown seaweeds of India / Food Chem 107 : 707 ~ 713
5. [학술지(정기간행물)] - Kang JY / 2008 / Antipyretic, analgesic, and anti-inflammatory activities of the seaweed Sargassum fulvellum and Sargassum thunbergii in mice / J Ethnopharmacol 116 : 187 ~ 190
2. [단행본] - Percival E / 1967 / Chemistry and enzymology of marine algal polysaccharides / Academic Press : 157 ~ 175
3. [학술지(정기간행물)] - Ruperez P / 2002 / Potential antioxidant capacity of sulfated polysaccharides from the edible marine brown seaweed Fucus vesiculosus / J Agric Food Chem 50 : 840 ~ 845
4. [학술지(정기간행물)] - Chandini SK / 2008 / In vitro antioxidant activities of three selected brown seaweeds of India / Food Chem 107 : 707 ~ 713
5. [학술지(정기간행물)] - Kang JY / 2008 / Antipyretic, analgesic, and anti-inflammatory activities of the seaweed Sargassum fulvellum and Sargassum thunbergii in mice / J Ethnopharmacol 116 : 187 ~ 190
이 논문의 저자 정보
이 논문과 함께 이용한 논문
국내 시판되는 적포도주의 항산화효과 및 항산화성분
최용민
,
유광원
,
한남수
외 2명
한국식품영양과학회지
2006
.11
벼 품종별 현미와 백미 70% 에탄올 추출물의 항산화 성분 및 항산화 효과
김대중
,
오세관
,
윤미라
한국식품영양과학회지
2010
.03
블루베리 첨가 막걸리의 발효특성
전미향
,
이원종
한국식품영양과학회지
2011
.03
오디씨로부터 항산화성 폴리페놀화합물의 분리 및 동정
이유진
,
김은옥
,
최상원
한국식품영양과학회지
2011
.04
포도씨 추출물과 분획물의 Tyrosinase 저해활성
한지영
,
성지혜
,
김대중
외 2명
한국식품영양과학회지
2008
.12
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2015-510-001091149