본 연구에서는 Lactobacillus brevis HLJ59 균주를 이용하여 오미자 당침액의 발효특성을 조사하였다. 발효에 따른 생균수와 PPH radical 소거활성, 환원력 및 SOD 유사활성을 조사하였다. 또한 오미자 당침액의 ACE 저해활성 및 Urease 저해활성을 조사하였다. 생균수의 경우 2배, 5배, 10배 희석액의 경우 2.05±0.21×10<SUP>8</SUP>, 6.31±0.56×10<SUP>11</SUP>, 8.14±0.14×10<SUP>9</SUP>으로 각각 조사되었으며, DPPH radical 소거활성은 2배, 5배, 10배 희석액의 경우 60.3%, 71.8%, 44.5%로 각각 조사되었다. 환원력은 2배, 5배, 10배 희석액의 경우 0.92, 1.19, 0.73 (700 nm에서의 OD값)로 각각 조사되었고, SOD 유사활성은 2배, 5배, 10배 희석액의 경우 50.4%, 53.7%, 33.4%로 각각 조사되었다. 그리고 ACE 저해활성 및 Urease 저해활성은 2배, 5배, 10배 희석액의 경우 47.4%, 78.2%, 56.4% 및 58.1%, 83.4%, 63.2%로 각각 조사되었다. 이상의 결과에서 오미자 당침 희석액 발효물은 우수한 항산화활성과 ACE 및 Urease 저해활성을 지님으로서 이를 기능성 식품소재로 활용할 수 있다고 사료된다.
This study was carried out to investigate the characteristics of FOST (fermented omija sugar treatment extracts) using Lactobacillus brevis HLJ59. Antioxidant activities of FOST were evaluated through viable cell number of L. brevis HLJ59, DPPH radical scavenging activity, reducing power and SOD-like activity, compared to non-FOST(non-fermented omija sugar treatment extracts). Also it was to evaluate Angiotensin Converting Enzyme (ACE) and Urease inhibitory activity of FOST. The viable cell number of L. brevis was about 2.05±0.21×10<SUP>8</SUP>, 6.31±0.56×10<SUP>11</SUP>, and 8.14±0.14×10<SUP>9</SUP> at ×2, ×5, and ×10 dilution, respectively. DPPH radical scavenging activity of FOST was about 60.3%, 71.8%, and 44.5% at ×2, ×5, and ×10 dilution, respectively. The reducing power of FOST was about 0.92, 1.19, and 0.73 (OD at 700 nm) at ×2, ×5, and ×10 dilution, and SOD-like activity of FOST was about 50.4%, 53.7%, and 33.4% at ×2, ×5, and ×10 dilution, respectively. ACE and Urease inhibitory activity by FOST was about 47.4%, 78.2%, 56.4% and 58.1%, 83.4%, 63.2% at ×2, ×5, and ×10 dilution, respectively. The results indicated that the fermentation of omija sugar treatment extracts using Lactobacillus brevis HLJ59 increased the antioxidant activities campared to the non-fermented omija sugar treatment extracts.