지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.12
- 수록면
- 667 - 672 (6page)
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초록· 키워드
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While imported falciparum malaria has been increasingly reported in recent years in Korea, clinicians have difficulties in making a clinical diagnosis as well as in having accessibility to effective anti-malarial agents. Here we describe an unusual case of imported falciparum malaria with severe hemolytic anemia lasting over 2 weeks, clinically mimicking a coinfection with babesiosis. A 48-year old Korean man was diagnosed with severe falciparum malaria in France after traveling to the Republic of Benin, West Africa. He received a 1-day course of intravenous artesunate and a 7-day course of Malarone (atovaquone/proguanil) with supportive hemodialysis. Coming back to Korea 5 days after discharge, he was readmitted due to recurrent fever, and further treated with Malarone for 3 days. Both the peripheral blood smears and PCR test were positive for Plasmodium falciparum. However, he had prolonged severe hemolytic anemia (Hb 5.6 g/dl). Therefore, 10 days after the hospitalization, Babesia was considered to be potentially coinfected. A 7-day course of Malarone and azithromycin was empirically started. He became afebrile within 3 days of this babesiosis treatment, and hemolytic anemia profiles began to improve at the completion of the treatment. He has remained stable since his discharge. Unexpectedly, the PCR assays failed to detect DNA of Babesia spp. from blood. In addition, during the retrospective review of the case, the artesunate-induced delayed hemolytic anemia was considered as an alternative cause of the unexplained hemolytic anemia.
목차
Abstract
INTRODUCTION
CASE REPORT
DISCUSSION
REFERENCES
참고문헌 (20)
참고문헌 신청
Center for Disease Control and Prevention, Republic of Korea / Epidemiologic characteristics of imported malaria in Korea, 2003-2012
Hae Suk Cheong / 2009 / Imported Malaria in Korea: a 13-Year Experience in a Single Center / The Korean Journal of Parasitology 47(3):299~302
안명희 / 2010 / 해외유입 기생충질환 / Infection and Chemotherapy 42(5):271~279
최원섭 / 2006 / 장간막 림프절염으로 발현된 Kikuchi-Fujimoto병 1예 / Infection and Chemotherapy 38(5):300~303
Veron V / 2009 / Multiplex real-time PCR detection of P. falciparum, P. vivax, and P. malariae in human blood samples / Exp Parasitol 121:346~351
Hae Suk Cheong / 2009 / Imported Malaria in Korea: a 13-Year Experience in a Single Center / The Korean Journal of Parasitology 47(3):299~302
안명희 / 2010 / 해외유입 기생충질환 / Infection and Chemotherapy 42(5):271~279
최원섭 / 2006 / 장간막 림프절염으로 발현된 Kikuchi-Fujimoto병 1예 / Infection and Chemotherapy 38(5):300~303
Veron V / 2009 / Multiplex real-time PCR detection of P. falciparum, P. vivax, and P. malariae in human blood samples / Exp Parasitol 121:346~351
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UCI(KEPA) : I410-ECN-0101-2016-513-001292050