지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
오류제보하기
Purpose: This study was aimed to identify the incidence and severity of chemotherapy-induced peripheral neuropathy (CIPN) among patients with hematologic malignancies and to examine the relationship between the quality of life (QOL) and CIPN. Methods: A total of 66 patients with CIPN-related symptoms participated in this study. Data were collected through self-reported questionnaires consisted of the European Organization for Research and Treatment of Cancer QLQ-C30 version 3.0 and the 16-item QLQ-CIPN20. Data were analyzed with SPSS/WIN20 for descriptive statistics using the Mann-Whitney and Kruskal-Wallis tests, and Spearman"s rho. Results: The mean lower and upper extremity scale scores were 31.95 and 23.16 respectively for the 16-item QLQ-CIPN20. The mean QLQ-C30 subcategory scores were 46.84 for global health status, 58.72 for functional scales, and 34.85 for symptom scales. The CIPN-related lower extremity scale symptoms correlated negatively with the QOL subscales. There was no correlation between CIPN-related upper extremity symptoms and health-related QOL. Conclusion: Patients with hematologic malignancies treated with neurotoxic chemotherapeutic agents had CIPN-related symptoms in the lower extremities mainly, and their QOL functional subscale scores were relatively lower than those of other cancer patients. Interventions need to be developed for patients with hematologic malignancies to alleviate CIPN and enhance their QOL.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
CONCLUSION
REFERENCES
참고문헌 (29)
참고문헌 신청
[학술지(정기간행물)] - Wickham R / 2007 / Chemotherapy-induced peripheral neuropathy : a review and implications for oncology nursing practice / Clinical Journal of Oncology Nursing 11 (3) : 361 ~ 376
[학술지(정기간행물)] - Postma TJ / 2005 / The development of an EORTC quality of life questionnaire to assess chemotherapy-induced peripheral neuropathy : the QLQ-CIPN20 / European Journal of Cancer 41 (8) : 1135 ~ 1139
[학술지(정기간행물)] - Tofthagen C. / 2010 / Patient perceptions associated with chemotherapy-induced peripheral neuropathy / Clinical Journal of Oncology Nursing 14 (3) : 22 ~ 28
[학술지(정기간행물)] - Ocean AJ / 2004 / Chemotherapy-induced peripheral neuropathy : pathogenesis and emerging therapies / Supportive Care in Cancer 12 (9) : 619 ~ 625
[학술지(정기간행물)] - Kautio AL / 2011 / Burden of chemotherapy-induced neuropathy-a cross-sectional study / Supportive Care in Cancer 19 (12) : 1991 ~ 1996
[학술지(정기간행물)] - Postma TJ / 2005 / The development of an EORTC quality of life questionnaire to assess chemotherapy-induced peripheral neuropathy : the QLQ-CIPN20 / European Journal of Cancer 41 (8) : 1135 ~ 1139
[학술지(정기간행물)] - Tofthagen C. / 2010 / Patient perceptions associated with chemotherapy-induced peripheral neuropathy / Clinical Journal of Oncology Nursing 14 (3) : 22 ~ 28
[학술지(정기간행물)] - Ocean AJ / 2004 / Chemotherapy-induced peripheral neuropathy : pathogenesis and emerging therapies / Supportive Care in Cancer 12 (9) : 619 ~ 625
[학술지(정기간행물)] - Kautio AL / 2011 / Burden of chemotherapy-induced neuropathy-a cross-sectional study / Supportive Care in Cancer 19 (12) : 1991 ~ 1996
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