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논문 기본 정보

자료유형
학술저널
저자정보
Nam-Woong Yang (Chosun University) Wan-Jin Sihn (Chosun University)
저널정보
대한미생물학회 JOURNAL OF BACTERIOLOGY AND VIROLOGY JOURNAL OF BACTERIOLOGY AND VIROLOGY Vol.45 No.3
발행연도
2015.9
수록면
228 - 234 (7page)

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초록· 키워드

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Bacterial vaginosis (BV) is the most frequent vaginal disease being apt to relapse. The growth inhibition effect of the mixture of citric acid (CA) and trisodium phosphate (TSP) on BV causative bacteria and probiotics was measured.Gardnerella vaginalis was reduced to zero in WCCT-1 (CA 0.25% and TSP 0.55% in Wilkins-Chalgren broth), 2.0 × 10⁴/ml in WCCT-2 (CA 0.5% and TSP 0.8% in WC), and 3.3 × 10³/ml in WCCT-3 (CA 1.0% and TSP 2.6% in WC) comparing with 1.3 × 10?/ml in WC after 48 h. Bacteroides fragilis was reduced to 6.0 × 10³/ml in WCCA (CA 0.34% in WC), 2.3 × 10²/ml in WCCT (CA 0.5% and TSP 0.2% in WC), 7.0 × 10³/ml in WCHCl (HCl in WC) after 48 h. Mobiluncus mulieris was reduced to 1.08 × 10⁴/ml in WCCA, 1.03 × 10³/ml in WCCT, and 10 ea/ml in WCHCl after 48 h. Peptostreptococcus asaccharolyticus was completely inhibited in WCCA, WCCT, and WCHCl after 24 h. Probiotics, Steroidobacter denitrificans YH1 (3.4 × 10?/ml) and Lactobacillus crispatus YH2 (2.7 × 10?/ml), grew to 1.25 × 10?/ml and 2.6 × 10?/ml in MRSCA (CA 1.0% in MRS), 1.8 × 10?/ml and 4.6 × 10?/ml in MRSCT (CA 1.5% and TSP 0.58% in MRS), 1.2 × 10?/ml and 2.3 × 10?/ml in MRSHCl after 48 h, respectively. These results mean that the CA-TSP mixture can be used as the useful vaginal pH controller, growth inhibitor on BV causative bacteria, and an efficient means for settlement of probiotics.

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INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES

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