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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- Korean Society for Precision Engineering Journal of the Korean Society for Precision Engineering Journal of the Korean Society for Precision Engineering Vol.33 No.1
- 발행연도
- 2016.1
- 수록면
- 63 - 67 (5page)
이용수
초록· 키워드
오류제보하기
We present a method of fabricating poly (lactic-co-glycolic acid) (PLGA) porous microfibers using a pore template. PLGA microfibers were synthesized using a glass capillary tube in a poly-(dimethylsiloxane) (PDMS) microfluidic chip. Gelatin solution was used as a porous template to prepare pores in microfibers. Two phases of PLGA solutions in different solvents-DMSO (dimethyl sulfoxide) and DCM (dichloromethane)-were used to control the porosity and strength of the porous microfibers. The porosity of the PLGA microfibers differed depending on the ratio of flow rates in the two phases. The porous structure was formed in a spiral shape on the microfiber. The porous structure of the microfiber is expected to improve transfer of oxygen and nutrients, which is important for cell viability in tissue engineering.
목차
1. 서론
2. 실험방법
3. 실험 결과 및 고찰
4. 결론
REFERENCES
참고문헌 (21)
참고문헌 신청
Khademhosseini, A., Langer, R., Borenstein, J., and Vacanti, J. P., “Microscale Technologies for Tissue Engineering and Biology,” Proc. of the National Academy of Sciences of the United States of America,Vol. 103, No. 8, pp. 2480-2487, 2006.
Mooney, D. J. and Vandenburgh, H., “Cell Delivery Mechanisms for Tissue Repair,” Cell Stem Cell, Vol. 2, No. 3, pp. 205-213, 2008.
Patrick Jr, C. W., Chauvin, P. B., Hobley, J., and Reece, G. P., “Preadipocyte Seeded PLGA Scaffolds for Adipose Tissue Engineering,” Tissue Engineering, Vol. 5, No. 2, pp. 139-151, 1999.
Holy, C. E., Cheng, C., Davies, J. E., and Shoichet, M. S., “Optimizing the Sterilization of PLGA Scaffolds for Use in Tissue Engineering,” Biomaterials, Vol. 22, No. 1, pp. 25-31, 2000.
Astete, C. E. and Sabliov, C. M., “Synthesis and Characterization of PLGA Nanoparticles,” Journal of Biomaterials Science, Vol. 17, No. 3, pp. 247-289, 2006.
Mooney, D. J. and Vandenburgh, H., “Cell Delivery Mechanisms for Tissue Repair,” Cell Stem Cell, Vol. 2, No. 3, pp. 205-213, 2008.
Patrick Jr, C. W., Chauvin, P. B., Hobley, J., and Reece, G. P., “Preadipocyte Seeded PLGA Scaffolds for Adipose Tissue Engineering,” Tissue Engineering, Vol. 5, No. 2, pp. 139-151, 1999.
Holy, C. E., Cheng, C., Davies, J. E., and Shoichet, M. S., “Optimizing the Sterilization of PLGA Scaffolds for Use in Tissue Engineering,” Biomaterials, Vol. 22, No. 1, pp. 25-31, 2000.
Astete, C. E. and Sabliov, C. M., “Synthesis and Characterization of PLGA Nanoparticles,” Journal of Biomaterials Science, Vol. 17, No. 3, pp. 247-289, 2006.
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UCI(KEPA) : I410-ECN-0101-2016-555-002308553