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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.6
- 수록면
- 215 - 222 (8page)
- DOI
- 10.17495/easdl.2016.6.26.3.215
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This study was carried out to investigate the antimicrobial and anti-inflammatory activities of ethanol extract from Glycyrrhizae radix (GR) and ethanol extract from Glycyrrhizae radix cultured with Paecilomyces japonica mycelium (GRPM). Antimicrobial activity was measured by paper disc diffusion assay and minimum inhibitory concentration (MIC). Antiinflammatory activity was evaluated by measurement of NO production in LPS-stimulated RAW264.7 cells. For the results of the paper disc diffusion assay, GRPM showed high antimicrobial activities against Bacillus cereus, Listeria monocytogenes, and Staphylococcus aureus. In addition, the MIC of GRPM (100 ppm) was lower than that of GR (200 ppm) against L. monocytogenes. When the morphology of L. monocytogenes treated with GRPM was observed using a FE-SEM, the surface of cells treated with GRPM were damaged, and some parts of the cell wall were destroyed. The inhibitory effect on NO production in LPS-stimulated RAW264.7 cells was significantly increased by GRPM treatment. In conclusion, GRPM is superior to GR in terms of antimicrobial and anti-inflammatory activities.
목차
ABSTRACT
서론
재료 및 방법
결과 및 고찰
요약 및 결론
REFERENCES
참고문헌 (32)
참고문헌 신청
[학술지(정기간행물)] - Ahn EY / 1998 / Isolation and identification of antimicrobial active substance from Glycyrrhiza uralensis Fisch / Korean J Food Sci Technol 30 : 680 ~ 687
[학술지(정기간행물)] - 박종필 / 2011 / Suppression of Inflammatory Macrophage Responese by Glycyrrhiza Uralensis Herbal Acupuncture Extract / Korean Journal of Acupuncture 28 (4) : 49 ~ 58
[학술지(정기간행물)] - Bauer AW / 1966 / Antibiotic susceptibility testing by a standardized single disk method / Am J Clin Pathol 45 : 493 ~ 496
[학술지(정기간행물)] - Carmichael J / 1987 / Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of chemosensitivity testing / Cancer Res 47 : 936 ~ 942
[학술지(정기간행물)] - Das SK / 2010 / Medicinal uses of the mushroom Cordyceps militaris: Current state and prospects / Fitoterapia 81 : 961 ~ 968
[학술지(정기간행물)] - 박종필 / 2011 / Suppression of Inflammatory Macrophage Responese by Glycyrrhiza Uralensis Herbal Acupuncture Extract / Korean Journal of Acupuncture 28 (4) : 49 ~ 58
[학술지(정기간행물)] - Bauer AW / 1966 / Antibiotic susceptibility testing by a standardized single disk method / Am J Clin Pathol 45 : 493 ~ 496
[학술지(정기간행물)] - Carmichael J / 1987 / Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of chemosensitivity testing / Cancer Res 47 : 936 ~ 942
[학술지(정기간행물)] - Das SK / 2010 / Medicinal uses of the mushroom Cordyceps militaris: Current state and prospects / Fitoterapia 81 : 961 ~ 968
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UCI(KEPA) : I410-ECN-0101-2017-594-000882133