지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.12
- 수록면
- 185 - 192 (8page)
이용수
초록· 키워드
오류제보하기
Although trimethoprim-sulfamethoxazole (TMP-SXT) is considered the first-line therapy for Stenotrophomonas maltophilia infections, there is debate on the use of the bacteriostatic drug in serious infections, and recently, there has been an increasing occurrence of acquired resistance to TMP-SXT. In the present study, the effect of efflux pump inhibitors on the susceptibility of TMP-SXT and other antibiotics were investigated in S. maltophilia complex. The sul and/or dfrA genes were identified in only up to 27.8% of all 36 TMP-SXT-resistant S. maltophilia complex isolates. Thus, TMP-SXT resistance in S. maltophilia was not explained completely by the presence of sul and dfrA genes. Carbonyl cyanide-m-chlorophenylhydrazone (CCCP) decreased the minimum inhibitory concentration (MIC) of TMP-SXT by eight to 128 folds in all 14 isolates. In contrast, 2,4-dinitrophenol (DNP), phenyl-arginine-β-naphthylamide (PAβN), and reserpine did not reduce the MIC of TMP-SXT. In addition to TMP-SXT, slight decrease in MICs was observed for tigecycline and piperacillin/tazobactam by CCCP (by two folds) in one isolate. Although efflux pump may play a role in TMP-SXT resistance in S. maltophilia, inhibition of the efflux pump could be done by active proton pore.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
A Case of Stenotrophomonas maltophilia Skin Infection at a Flap Site
대한의진균학회지
2021 .01
-
Performance test of a Cryo-TMP combination pump
한국진공학회 학술발표회초록집
2016 .08
-
CWP(cryogenic water pump)와 TMP를 결합한 복합펌프의 활용과 전망
한국진공학회 학술발표회초록집
2018 .08
-
Clinical Examination of Stenotrophomonas maltophilia Infection in Patient with Pyoderma Gangrenosum
대한의진균학회지
2023 .03
-
A Colistin-degrading Protease from the Opportunistic Pathogen Stenotrophomonas maltophilia Confers Collective Resistance in Polymicrobial Infection Communities
한국미생물학회 학술대회논문집
2022 .10
-
A Destruction Pattern Analysis of a Turbo-Molecular Pump According to the Foreline Clamp Damage in an ICP Dry Etcher for 300 mm Wafers
Applied Science and Convergence Technology
2015 .03
-
Box-Behnken Design을 이용한 수용액 중의 Trimethoprim에 대한 폐감귤박 자성활성탄의 흡착 특성
한국환경과학회지
2022 .08
-
Immobilization of Alcohol Dehydrogenase in Membrane: Fouling Mechanism at Different Transmembrane Pressure
대한화학회지
2019 .08
-
Antiferromagnetic Van der Waals materials TMPS₃ and its Potentials
한국자기학회 학술연구발표회 논문개요집
2019 .05
-
RND efflux pump systems in Acinetobacter, with special emphasis on their role in quorum sensing
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2019 .03
-
Characterization of Trimethoprim-Sulfamethoxazole Resistance Genes and Their Relatedness to Class 1 Integron and Insertion Sequence Common Region in Gram-Negative Bacilli
Journal of Microbiology and Biotechnology
2015 .01
-
Structural Architecture of Multidrug Efflux Pumps and Type I Secretion Systems from Gram-negative Bacteria
한국미생물학회 학술대회논문집
2016 .04
-
Cloning and functional characterization of putative Escherichia coli ABC multidrug efflux transporter YddA
Journal of Microbiology and Biotechnology
2020 .01
-
Indole-induced Activities of β-Lactamase and Efflux Pump Confer Ampicillin Resistance in Pseudomonas putida KT2440
한국미생물학회 학술대회논문집
2017 .04
-
중·대형 터보분자펌프 특성 평가 시스템 개발
한국진공학회 학술발표회초록집
2021 .02
-
Role of folP1 and folP2 Genes in the Action of Sulfamethoxazole and Trimethoprim Against Mycobacteria
Journal of Microbiology and Biotechnology
2015 .01
-
Binary Truncated Moment Problems and the Hadamard Product
East Asian Mathematical Journal
2020 .01
-
Role of ppGpp-regulated Efflux Genes in Acinetobacter baumannii
한국미생물학회 학술대회논문집
2020 .10
-
Role of ppGpp-regulated Efflux Genes in Acinetobacter baumannii
한국미생물학회 학술대회논문집
2020 .10
-
CONSISTENCY AND GENERAL TRUNCATED MOMENT PROBLEMS
충청수학회지
2018 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2017-475-002003432