지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.2
- 수록면
- 20 - 24 (5page)
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초록· 키워드
오류제보하기
A symbiotic relationship between humans and the microbiota is critical for the maintenance of our health, including
development of the immune system, enhancement of the epithelial barrier, and acquisition of nutrients. Recent
research has shown that the microbiota impacts immune cell development and differentiation. These findings suggest
that the microbiota may also influence adjuvant and vaccine efficacy. Indeed, several factors such as malnutrition
and poor sanitation, which affect gut microbiota composition, impair the efficacy of vaccines. Although there is
little evidence that microbiota alters vaccine efficacy, further understanding of human immune system-microbiota
interactions may lead to the effective development of adjuvants and vaccines for the treatment of diseases.
목차
INTRODUCTION
Microbiot a influences vaccine efficacy
Gut microbiot a provides a source of natural adjuvants
Nasal microbiot a-derived component enhances mucosal adjuvant efficacy
Concluding Remarks
REFERENCES
참고문헌 (38)
참고문헌 신청
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McKenney, P. T., and E. G. Pamer. 2015. From hype to hope: The gut microbiota in enteric infectious disease. Cell 163: 1326-1332.
Tanoue, T., K. Atarashi, and K. Honda. 2016. Development and maintenance of intestinal regulatory T cells. Nat. Rev. Immunol. 16: 295-309.
Belkaid, Y., and T. W. Hand. 2014. Role of the microbiota in immunity and inflammation. Cell 157: 121-141.
Round, J. L., and S. K. Mazmanian. 2009. The gut microbiota shapes intestinal immune responses during health and disease. Nat. Rev. Immunol. 9: 313-323.
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Revolutionizing gut health: exploring the role of gut microbiota and the potential of microbiome-based therapies in lower gastrointestinal diseases
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UCI(KEPA) : I410-ECN-0101-2017-517-002233579