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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.9
- 수록면
- 165 - 170 (6page)
이용수
초록· 키워드
오류제보하기
The skin functions as a physical barrier against entry of pathogens while concomitantly supporting a myriad of commensal organisms. The characterization of these microbial communities has enhanced our knowledge of the ecology of organisms present in normal skin, and studies have begun to illuminate the intimate relationship between the host and resident microbes. The cutaneous innate and adaptive immune responses can modulate skin microbiota, while simultaneously, the microbiota educates the host immune system. A crucial element of the innate immune response is mast cells, which reside strategically in tissues that are commonly exposed to the external environment, such as the skin and mucosae. Mast cells are present on the frontline of defense against pathogens, suggesting they may play an important role in fostering the host-microbiota relationship. In this review, we highlight findings regarding the interaction between skin microbiota and mast cells and the resulting outcomes in skin homeostasis.
목차
INTRODUCTION
SKIN MICROBIOME AND IMMUNE TOLERNACE
SKIN MICROBIOME AND MAST CELL MATURATION
SKIN MICROBIOME AND MAST CELL ANTIVIRAL ACTIVITY
SKIN INFLAMMATORY DISEASE
CLOSING REMARKS
REFERENCES
참고문헌 (29)
참고문헌 신청
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Takemoto A, Cho O, Morohoshi Y, Sugita T, Muto M. Molecular characterization of the skin fungal microbiome in patients with psoriasis. J Dermatol 2015;42: 166-70.
Nada HA, Gomaa NI, Elakhras A, Wasfy R, Baker RA. Skin colonization by superantigen-producing Staphylococcus aureus in Egyptian patients with atopic dermatitis and its relation to disease severity and serum interleukin- 4 level. Int J Infect Dis 2012;16:e29-33.
Csaba G. Mast cell, the peculiar member of the immune system: A homeostatic aspect. Acta Microbiol Immunol Hung 2015;62:207-31.
Forsythe P, Bienenstock J. The mast cell-nerve functional unit: a key component of physiologic and pathophysiologic responses. Chem Immunol Allergy 2012;98:196 -221.
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UCI(KEPA) : I410-ECN-0101-2018-475-001332056