Perianal Paget disease: a report of 2 cases

Youn Young Park; Moonsik Kim; Chinock Cheong; Sang Kyum Kim; Seung Yong Song; Kee-Yang Chung; Nam Kyu Kim

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자료유형: 학술저널

저자정보: Youn Young Park (Yonsei University College of Medicine) Moonsik Kim (Yonsei University College of Medicine) Chinock Cheong (Yonsei University College of Medicine) Sang Kyum Kim (Yonsei University College of Medicine) Seung Yong Song (Yonsei University College of Medicine) Kee-Yang Chung (Yonsei University College of Medicine) Nam Kyu Kim (Yonsei University College of Medicine)

저널정보: 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.93 No.6

발행연도: 2017.12

수록면: 336 - 341 (6page)

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Extramammary Paget disease (EMPD) is a rare cutaneous neoplasm. Perianal Paget disease (PPD) is a subset of EMPD manifesting perianal lesions. Two cases of PPD in Severance Hospital are described in this article. A 65-year-old female and 78-year-old male patients visited our institution because of an unhealed perianal skin lesion despite treatment for a long period with topical agents. PPD was diagnosed by skin biopsies in both cases, and the patients underwent surgical treatment. Clinical manifestations, preoperative work-ups, and surgical treatments including different reconstruction methods are described in detail. As only sporadic PPD cases have been reported and no standard treatment has been established, we hope that our experience could contribute to improving the diagnosis and treatment of PPD patients.

#Extramammary Paget disease

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참고문헌 신청

Perez DR, Trakarnsanga A, Shia J, Nash GM, Temple LK, Paty PB, et al. Management and outcome of perianal Paget's disease: a 6-decade institutional experience. Dis Colon Rectum 2014;57:747- 51. Minicozzi A, Borzellino G, Momo R, Steccanella F, Pitoni F, de Manzoni G. Perianal Paget's disease: presentation of six cases and literature review. Int J Colorectal Dis 2010;25:1-7. Herrel LA, Weiss AD, Goodman M, Johnson TV, Osunkoya AO, Delman KA, et al. Extramammary Paget's disease in males: survival outcomes in 495 patients. Ann Surg Oncol 2015;22:1625-30. Moller MG, Lugo-Baruqui JA, Milikowski C, Salgado CJ. Staged marginal contoured and central excision technique in the surgical management of perianal Paget's disease. Am J Surg 2014;207:485-92. Nowak MA, Guer r iere-Kovach P, Pathan A, Campbell TE, Deppisch LM. Perianal Paget's disease: distinguishing primary and secondary lesions using immunohistochemical studies including gross cystic disease fluid protein-15 and cytokeratin 20 expression. Arch Pathol Lab Med 1998;122:1077-81.

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