지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.12
- 수록면
- 102 - 108 (7page)
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초록· 키워드
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Purpose: Studies investigating the appropriate post-surgery follow-up method for elderly patients with colorectal cancer are limited. Thus, the purpose of this study was to compare survival rates between two follow-up methods in patients aged 80 years or older who underwent surgery for colorectal cancer.
Methods: Between January 1, 2002 and December 31, 2010, 165 patients aged 80 years or older underwent curative resection for non-metastatic colorectal cancer at the Department of Surgery, Seoul National University Hospital. Sixty-six of these patients were excluded due to the lack of follow-up, while the remaining 99 were included in our study. These 99 patients were divided into the following two groups depending on their post-surgery follow-up method. Patients who underwent follow-up on a regular basis, which was defined as once every six months to one year, with carcinoembryonic antigen (CEA) and computed tomography (CT) comprised the Regular group, and those who received follow-up with CEA alone or underwent CT procedures once every two years or more comprised the Minimal group. Overall survival was analyzed with the log-rank test and Cox regression analysis.
Results: Of the 99 patients, 62 were in Regular group and 37 were in Minimal group. There was no difference in overall survival rate between the two post-surgery follow-up methods (regular group vs. minimal group: 51.6% vs. 50.9% [5-year overall survival rate], P=0.819). Additionally, no significant differences was detected between the groups following multivariate analysis (harzard ratio=0.907; 95% confidence interval=0.460–1.788, P=0.777).
Conclusion: A significant survival gain was not observed between Regular and Minimal group. To draw a more definite conclusion, a multi-center randomized research study should be conducted.
Methods: Between January 1, 2002 and December 31, 2010, 165 patients aged 80 years or older underwent curative resection for non-metastatic colorectal cancer at the Department of Surgery, Seoul National University Hospital. Sixty-six of these patients were excluded due to the lack of follow-up, while the remaining 99 were included in our study. These 99 patients were divided into the following two groups depending on their post-surgery follow-up method. Patients who underwent follow-up on a regular basis, which was defined as once every six months to one year, with carcinoembryonic antigen (CEA) and computed tomography (CT) comprised the Regular group, and those who received follow-up with CEA alone or underwent CT procedures once every two years or more comprised the Minimal group. Overall survival was analyzed with the log-rank test and Cox regression analysis.
Results: Of the 99 patients, 62 were in Regular group and 37 were in Minimal group. There was no difference in overall survival rate between the two post-surgery follow-up methods (regular group vs. minimal group: 51.6% vs. 50.9% [5-year overall survival rate], P=0.819). Additionally, no significant differences was detected between the groups following multivariate analysis (harzard ratio=0.907; 95% confidence interval=0.460–1.788, P=0.777).
Conclusion: A significant survival gain was not observed between Regular and Minimal group. To draw a more definite conclusion, a multi-center randomized research study should be conducted.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (10)
참고문헌 신청
[학술지(정기간행물)] - 정규원 / 2017 / Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2014 / Cancer Research and Treatment 49 (2) : 292 ~ 305
[학술지(정기간행물)] - Kim IK / 1999 / Population aging in Korea: social problems and solutions / J Sociol Soc Welf 26 : 107 ~ 123
[학술지(정기간행물)] - Buie WD / 2005 / Follow-up recommendations for colon cancer / Clin Colon Rectal Surg 18 : 232 ~ 243
[학술지(정기간행물)] - Steele SR / 2015 / Practice guideline for the surveillance of patients after curative treatment of colon and rectal cancer / Dis Colon Rectum 58 : 713 ~ 725
[학술지(정기간행물)] - Peng Y / 2015 / Role of blood tumor markers in predicting metastasis and local recurrence after curative resection of colon cancer / Int J Clin Exp Med 8 : 982 ~ 990
[학술지(정기간행물)] - Kim IK / 1999 / Population aging in Korea: social problems and solutions / J Sociol Soc Welf 26 : 107 ~ 123
[학술지(정기간행물)] - Buie WD / 2005 / Follow-up recommendations for colon cancer / Clin Colon Rectal Surg 18 : 232 ~ 243
[학술지(정기간행물)] - Steele SR / 2015 / Practice guideline for the surveillance of patients after curative treatment of colon and rectal cancer / Dis Colon Rectum 58 : 713 ~ 725
[학술지(정기간행물)] - Peng Y / 2015 / Role of blood tumor markers in predicting metastasis and local recurrence after curative resection of colon cancer / Int J Clin Exp Med 8 : 982 ~ 990
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UCI(KEPA) : I410-ECN-0101-2018-514-001685043