Oncologic outcomes after radical surgery for periampullary cancer in octogenarians

Sung Hyun Kim; Jae Uk Chong; Jin Hong Lim; Moon Jae Chung; Jeong Youp Park; Seung Min Bang; Seung Woo Park; Ho Kyung Hwang; Chang Moo Kang; Woo Jung Lee; Kyung Sik Kim

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자료유형: 학술저널

저자정보: Sung Hyun Kim (Yonsei University College of Medicine) Jae Uk Chong (Yonsei University College of Medicine) Jin Hong Lim (Yonsei University College of Medicine) Moon Jae Chung (Yonsei University College of Medicine) Jeong Youp Park (Yonsei University College of Medicine) Seung Min Bang (Yonsei University College of Medicine) Seung Woo Park (Yonsei University College of Medicine) Ho Kyung Hwang (Yonsei University College of Medicine) Chang Moo Kang (Yonsei University College of Medicine) Woo Jung Lee (Yonsei University College of Medicine) Kyung Sik Kim (Yonsei University College of Medicine)

저널정보: 한국간담췌외과학회 Annals of Hepato-Biliary-Pancreatic Surgery 한국간담췌외과학회지 제22권 제2호

발행연도: 2018.5

수록면: 128 - 135 (8page)

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Backgrounds/Aims: Interest in treatments for elderly patients has increased with life expectancy, and various studies have reported on the safety and feasibility of radical surgery in elderly patients with cancer. Here, we investigated oncologic outcomes of periampullary cancer in octogenarians. Methods: We retrospectively reviewed medical records of 68 patients over 80 years of age who were diagnosed with periampullary cancer and were eligible for surgery; we analyzed overall survival (OS) and immediate postoperative complications and mortality. Results: There were no significant differences in mean age, disease type, oncologic features, comorbidities, or nutritional status between the patients who had surgery and those who did not. Five patients (20.0%) had major postoperative complications, but there was no immediate postoperative mortality. Patients who had surgery (n=25) had better OS (29.3 months; 95% confidence interval [CI]: 5.6-53.0) than did those who did not (n=43, OS: 7.6 months; 95% CI: 3.2-12.0 months; p ＜0.001). Similarly, patients with distal common bile duct cancer who underwent surgery had better OS than those who did not (surgery group: n=13, OS: 29.3 months, 95% CI: 8.9-49.7; non-surgery group: n=15, OS: 5.7 months, 95% CI: 4.2-7.2 months; p=0.002). Conclusions: Radical surgery for octogenarian patients with periampullary cancer is safe, feasible, and expected to result in better survival outcomes, especially for patients with common bile duct cancer.

#Periampullary cancer #Octogenarian #Radical surgery #Oncologic outcome #Complication

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