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자료유형
학술저널
저자정보
저널정보
한국식품저장유통학회 Food Science and Preservation 한국식품저장유통학회지 제20권 제6호
발행연도
2013.12
수록면
877 - 885 (9page)

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Wine extracts of four different berry fruits, such as mulberry, blueberry, strawberry, and raspberry, were investigated for antioxidant, anti-tyrosinase, and α-glucosidase activities by using in vitro assays. Additionally, quantitative changes of α-glucosidase inhibitor in mulberry wine were determined by HPLC according to mulberry cultivars and fermentation process. Among four berry wines examined, mulberry wine showed the most potent α-glucosidase inhibitory activity with 69.37% at 0.23 mg/mL, while blueberry and strawberry wines exhibited the strongest inhibition against DPPH radical and tyrosinase activity, respectively. Four compounds were isolated and purified from mulberry wine by a series of isolation procedures, such as solvent fractionation, and Diaion HP-20, ODS-A, and Sephadex LH-20 column chromatographies. Among them, Comp. 4 exerted the strongest α-glucosidase inhibitory activity (IC<SUB>50</SUB>=31.57 μM), and its chemical structure was identified as quercetin by UV and NMR spectral analysis. Finally, the “Daeseongppong” (16.83 ppm) muberry wine had larger amount of quercetin than the “Iksuppong” (14.85 ppm) and “Cheongilppong” (8.92 ppm) mulberry wines, but their contents of three mulberry wines decreased considerably with aging process. These results suggest that mulberry wine containing quercetin acted as α-glucosidase inhibitor may be useful as a potential functional wine for improving diabetic disorder.

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UCI(KEPA) : I410-ECN-0101-2018-059-003067847