지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.95 No.6
- 발행연도
- 2018.12
- 수록면
- 324 - 332 (9page)
이용수
초록· 키워드
오류제보하기
Purpose: We present our experience involving the management of this disease, identifying prognostic factors affecting treatment outcomes.
Methods: The patients treated for Fournier gangrene at our institution were retrospectively reviewed. Data collected included demographics, extent of soft tissue necrosis, predisposing factors, etiological factors, laboratory values, and treatment outcomes. The severity index and score were calculated. Multivariate regression analysis was used to determine the association between potential predictors and clinical outcomes.
Results: A total of 41 patients (male:female = 33:8) were studied. The mean age was 54.4 years (range, 24-79 years). The most common predisposing factor was diabetes mellitus (n = 19, 46.3%). Sixteen patients (39.0%) were current smokers. Seven patients had chronic kidney disease. The most frequent etiology was urogenital lesion (41.5%). The mortality rate was 22.0% (n = 9). Multivariate regression analyses showed that extension of necrosis beyond perineal/inguinal area and pre-existing chronic kidney disease were significant and independent predictors of mortality. Extension of necrosis beyond perineal/inguinal area was a significant predictor of increased duration in the intensive care unit and hospital stay. In addition, pre-existing chronic kidney disease was a significant predictor of flap reconstruction in the wound.
Conclusion: Fournier gangrene with extensive soft tissue necrosis and pre-existing chronic kidney disease was associated with poor prognosis and complexity of patient management. Early recognition of dissemination and premorbid renal function is essential to reduce mortality and establish a management plan for this disease.
Methods: The patients treated for Fournier gangrene at our institution were retrospectively reviewed. Data collected included demographics, extent of soft tissue necrosis, predisposing factors, etiological factors, laboratory values, and treatment outcomes. The severity index and score were calculated. Multivariate regression analysis was used to determine the association between potential predictors and clinical outcomes.
Results: A total of 41 patients (male:female = 33:8) were studied. The mean age was 54.4 years (range, 24-79 years). The most common predisposing factor was diabetes mellitus (n = 19, 46.3%). Sixteen patients (39.0%) were current smokers. Seven patients had chronic kidney disease. The most frequent etiology was urogenital lesion (41.5%). The mortality rate was 22.0% (n = 9). Multivariate regression analyses showed that extension of necrosis beyond perineal/inguinal area and pre-existing chronic kidney disease were significant and independent predictors of mortality. Extension of necrosis beyond perineal/inguinal area was a significant predictor of increased duration in the intensive care unit and hospital stay. In addition, pre-existing chronic kidney disease was a significant predictor of flap reconstruction in the wound.
Conclusion: Fournier gangrene with extensive soft tissue necrosis and pre-existing chronic kidney disease was associated with poor prognosis and complexity of patient management. Early recognition of dissemination and premorbid renal function is essential to reduce mortality and establish a management plan for this disease.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (20)
참고문헌 신청
[학술지(정기간행물)] - Eke N / 2000 / Fournier's gangrene : a review of 1726 cases / Br J Surg 87 : 718 ~ 728
[학술지(정기간행물)] - Yanar H / 2006 / Fournier's gangrene : risk factors and strategies for management / World J Surg 30 : 1750 ~ 1754
[학술지(정기간행물)] - Laor E / 1995 / Outcome prediction in patients with Fournier's gangrene / J Urol 154 : 89 ~ 92
[학술지(정기간행물)] - Wong CH / 2004 / The LRINEC(Laboratory Risk Indicator for Necrotizing Fasciitis)score : a tool for distinguishing necrotizing fasciitis from other soft tissue infections / Crit Care Med 32 : 1535 ~ 1541
[학술지(정기간행물)] - Altarac S / 2012 / Fournier's gangrene : etiology and outcome analysis of 41patients / Urol Int 88 : 289 ~ 293
[학술지(정기간행물)] - Yanar H / 2006 / Fournier's gangrene : risk factors and strategies for management / World J Surg 30 : 1750 ~ 1754
[학술지(정기간행물)] - Laor E / 1995 / Outcome prediction in patients with Fournier's gangrene / J Urol 154 : 89 ~ 92
[학술지(정기간행물)] - Wong CH / 2004 / The LRINEC(Laboratory Risk Indicator for Necrotizing Fasciitis)score : a tool for distinguishing necrotizing fasciitis from other soft tissue infections / Crit Care Med 32 : 1535 ~ 1541
[학술지(정기간행물)] - Altarac S / 2012 / Fournier's gangrene : etiology and outcome analysis of 41patients / Urol Int 88 : 289 ~ 293
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UCI(KEPA) : I410-ECN-0101-2019-514-000192514