지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.12
- 수록면
- 1,930 - 1,934 (5page)
- DOI
- 10.13000/JFMSE.2018.12.30.6.1930
이용수
초록· 키워드
오류제보하기
The study was aimed at investigating the pharmacokinetics of erythromycin thiocyanate(EM) in the cultured olive flounder(Paralichthys olivaceus) following single intramuscular administration, using LC/MS/MS following. After single administration of EM(5 and 10 mg/kg body weight) by intramuscular injection in olive flounder(332±20 g, 20±0.5℃), the EM concentration in the serum was determined at 1, 3, 6, 9, 24, 72, 120, 168, 264, 360, 504 and 720 h post-dose, respectively. The kinetic profile of EM intramuscular administration in serum were analyzed fitting to a non-compartment model by WinNonlin program. The residual pattern of EM was immediately decreased on after single administration. Concentrations of EM were not measurable at 168 hours (7 days) after intramuscular administration in all samples. The results of this study could be used for determining withdrawal time and efficacy dose of EM for the treatment of bacterial diseases in culturing olive flounder.
목차
Abstract
Ⅰ. 서론
Ⅱ. 재료 및 방법
Ⅲ. 결과 및 고찰
References
참고문헌 (14)
참고문헌 신청
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[학술지(정기간행물)] - JH Creeper / 2006 / An outbreak of Streptococcus iniae in barramundi (Lates calcarifera) in freshwater cage culture / Australian Veterinary Journal 84 (11) : 408 ~ 411
[학술지(정기간행물)] - Esposito A / 2007 / Orally Administered Erythromycin in Rainbow Trout (Oncorhynchus mykiss): Residues in Edible Tissues and Withdrawal Time / Antimicrobial Agents and Chemotherapy 51 (3) : 1043 ~ 1047
[학술지(정기간행물)] - Katae H / 1980 / Studies on Chemotherapy of Fish Disease with Erythromycin-I / Fish Pathology 15 (1) : 7 ~ 16
[기타자료] - KFDA / 2017 / MRLs for veterinary drugs in foods / : 1 ~ 729
[학술지(정기간행물)] - JH Creeper / 2006 / An outbreak of Streptococcus iniae in barramundi (Lates calcarifera) in freshwater cage culture / Australian Veterinary Journal 84 (11) : 408 ~ 411
[학술지(정기간행물)] - Esposito A / 2007 / Orally Administered Erythromycin in Rainbow Trout (Oncorhynchus mykiss): Residues in Edible Tissues and Withdrawal Time / Antimicrobial Agents and Chemotherapy 51 (3) : 1043 ~ 1047
[학술지(정기간행물)] - Katae H / 1980 / Studies on Chemotherapy of Fish Disease with Erythromycin-I / Fish Pathology 15 (1) : 7 ~ 16
[기타자료] - KFDA / 2017 / MRLs for veterinary drugs in foods / : 1 ~ 729
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UCI(KEPA) : I410-ECN-0101-2019-454-000146813