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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.8
- 수록면
- 408 - 411 (4page)
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초록· 키워드
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Purpose: This study investigated the effect of bioactive Yeonsan Ogye peptides (YOPs) intake on changes in the hepatic anti-oxidant indexes in male rats. Methods: Sprague-Dawley male rats were divided into 3 groups and given a casein-based AIN-93G diet and distilled water ad libitum without any added YOPs (control), distilled water with 250 mg of YOPs (Y250), or 500 mg of YOPs (Y500) per kg of body weight for 4 weeks. YOP dose was decided as referred to in the referenced study where toxicity did not occur. The hepatic anti-oxidant indexes were determined using a commercial kit. Statistical analysis was performed using SPSS version 23.0 and are expressed as mean ±standard error of mean. Differences among the groups were evaluated by one-way analysis of variance followed by post hoc Duncan’s multiple comparisons test. Results: There were no differences in the body weights, weight gain, food intake, food efficiency ratio, or organ weight, including liver, kidney, spleen, thymus, and epididymal fat, among all of the groups. The hepatic nitric oxide (NO) level in the Y500 group was lower than that in the control and Y250 groups, and the hepatic malondialdehyde (MDA) level was lower in the Y500 group than in the Y250 group. The differences in hepatic superoxide dismutase (SOD) and catalase (CAT) activities were not statistically significant between the groups. From these results we speculated that YOPs may have anti-oxidative abilities to regulate NO and MDA production without affecting SOD and CAT activities. Conclusion: YOPs are presumed to act as anti-oxidants in the animal or human body.
목차
ABSTRACT
Introduction
Methods
Results and Discussion
References
참고문헌 (12)
참고문헌 신청
Han SW / 1996 / Present status of research and commercial production of Korean Ogol chicken / Korea J Poult Sci 23(3):145~151
Heo J / 2007 / Dongui bogam / Bubin Publishers Co
김진우 / 2015 / 동의보감에 수재된 烏鷄에 대한 생리활성 연구 / 대한본초학회지 30(5):23~28
Kitts DD / 2003 / Bioactive proteins and peptides from food sources. Applications of bioprocesses used in isolation and recovery / Curr Pharm Des 9(16):1309~1323
Udenigwe CC / 2012 / Food protein-derived bioactive peptides : production, processing, and potential health benefits / J Food Sci 77(1):R11~R24
Heo J / 2007 / Dongui bogam / Bubin Publishers Co
김진우 / 2015 / 동의보감에 수재된 烏鷄에 대한 생리활성 연구 / 대한본초학회지 30(5):23~28
Kitts DD / 2003 / Bioactive proteins and peptides from food sources. Applications of bioprocesses used in isolation and recovery / Curr Pharm Des 9(16):1309~1323
Udenigwe CC / 2012 / Food protein-derived bioactive peptides : production, processing, and potential health benefits / J Food Sci 77(1):R11~R24
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