지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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Purpose: Many studies have examined the mechanisms of impaired glucose homeostasis after organophosphate (OP) exposure, however no study has evaluated the clinical utility of blood glucose measurements in patients with OP poisoning. The current study was conducted to evaluate the initial glucose level at presentation and the glycemic variables during the first 3 days after admission as a predictor of mortality.
Methods: This retrospective observational case series included 228 patients with a history of OP poisoning. Among other clinical data, information on the initial glucose level at presentation and mean glucose level, delta glucose level, and the presence of a hypoglycemic event during the first 3 days of admission, was collected.
Results: Survivors had lower initial glucose levels at presentation and glucose variability during the first 3 days of admission compared to non-survivors. The frequency of hypoglycemic events was higher in non-survivors. In multivariate analysis, the initial glucose level (> 233 mg/dl) was an independent predictor of mortality, along with age.
Conclusion: The initial glucose level at presentation can be helpful in prediction of mortality in cases of OP intoxication at bedside. The physician should pay attention to patients with a glucose level >233 mg/dl at presentation after ingestion of OP.
목차
등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
Mehrpour O / 2008 / Hyperglycemia in acute aluminum phosphide poisoning as a potential prognostic factor / Hum Exp Toxicol 27:591~595
Sanaei-Zadeh H / 2011 / Hyperglycemia is a strong prognostic factor of lethality in methanol poisoning / J Med Toxicol 7:189~194
Su G / 2013 / Impact of admission glycemic variability, glucose, and glycosylated hemoglobin on major adverse cardiac events after acute myocardial infarction / Diabetes Care 36:1026~1032
Mendez CE / 2013 / Increased glycemic variability is independently associated with length of stay and mortality in noncritically ill hospitalized patients / Diabetes Care 36:4091~4097
Krinsley JS / 2009 / Glycemic variability and mortality in critically ill patients : the impact of diabetes / J Diabetes Sci Technol 3:1292~1301
Sanaei-Zadeh H / 2011 / Hyperglycemia is a strong prognostic factor of lethality in methanol poisoning / J Med Toxicol 7:189~194
Su G / 2013 / Impact of admission glycemic variability, glucose, and glycosylated hemoglobin on major adverse cardiac events after acute myocardial infarction / Diabetes Care 36:1026~1032
Mendez CE / 2013 / Increased glycemic variability is independently associated with length of stay and mortality in noncritically ill hospitalized patients / Diabetes Care 36:4091~4097
Krinsley JS / 2009 / Glycemic variability and mortality in critically ill patients : the impact of diabetes / J Diabetes Sci Technol 3:1292~1301
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