지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 393 - 401 (9page)
이용수
초록· 키워드
오류제보하기
Background/Aims: Current guidelines recommend withholding antiplatelets for 5–7 days before high-risk endoscopic procedures. We investigated whether this reduces post-endoscopic submucosal dissection (ESD) bleeding. Methods: Gastric ESD cases with antiplatelets were retorospectively reviewed. Withholding antiplatelets for 5–7 days before ESD was defined as cessation and 0–4 days as continuation. The rate and risk of post-ESD bleeding according to the types and cessation of antiplatelets were assessed. Results: Among the 215 patients (117 adenoma and 98 early gastric cancer), 161 patients were on single (94 aspirin, 56 thienopyridine, and 11 other agents), 51 on dual, and 3 on triple antiplatelets. Post-ESD bleeding rates were 12.8% in aspirin users, 3.6% in thienopyridine, 27.5% in dual, 33.3% in triple therapy, and 9.7% in the cessation and 15.0% in the continuation group. Multiple antiplatelets (odds ratio [OR], 2.41; 95% confidence interval [CI], 1.01 to 5.76) and specimen size ≥ 5.5 cm (OR, 2.84; 95% CI, 1.04 to 7.73) were the risk of bleeding, while continuation of thienopyridine (OR, 0.23; 95% CI, 0.05 to 1.09) and antiplatelets (OR, 1.83; 95% CI, 0.68 to 4.94) did not increase the risk of bleeding. Conclusions: Continuing thienopyridine and aspirin did not increase the risk of post-ESD. Multiple antiplatelet therapy and a large specimen size were independent risk factors of post-ESD bleeding.
목차
등록된 정보가 없습니다.
참고문헌 (30)
참고문헌 신청
Oda I / 2013 / Complications of gastric endoscopic submucosal dissection / Dig Endosc 25(Suppl 1):71~78
Toyonaga T / 2013 / 1,635 Endoscopic submucosal dissection cases in the esophagus, stomach, and colorectum: complication rates and long-term outcomes / Surg Endosc 27:1000~1008
Lim JH / 2012 / Do antiplatelets increase the risk of bleeding after endoscopic submucosal dissection of gastric neoplasms? / Gastrointest Endosc 75:719~727
Cho SJ / 2012 / Aspirin use and bleeding risk after endoscopic submucosal dissection in patients with gastric neoplasms / Endoscopy 44:114~121
Koh R / 2013 / Antithrombotic drugs are risk factors for delayed postoperative bleeding after endoscopic submucosal dissection for gastric neoplasms / Gastrointest Endosc 78:476~483
Toyonaga T / 2013 / 1,635 Endoscopic submucosal dissection cases in the esophagus, stomach, and colorectum: complication rates and long-term outcomes / Surg Endosc 27:1000~1008
Lim JH / 2012 / Do antiplatelets increase the risk of bleeding after endoscopic submucosal dissection of gastric neoplasms? / Gastrointest Endosc 75:719~727
Cho SJ / 2012 / Aspirin use and bleeding risk after endoscopic submucosal dissection in patients with gastric neoplasms / Endoscopy 44:114~121
Koh R / 2013 / Antithrombotic drugs are risk factors for delayed postoperative bleeding after endoscopic submucosal dissection for gastric neoplasms / Gastrointest Endosc 78:476~483
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