지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아내분비학회 Annals of Pediatirc Endocrinology & Metabolism Annals of Pediatirc Endocrinology & Metabolism 제20권 제3호
- 발행연도
- 2015.1
- 수록면
- 155 - 161 (7page)
이용수
초록· 키워드
오류제보하기
Purpose: In male patients with congenital adrenal hyperplasia (CAH), the presence of testicular adrenal rest tumors (TARTs) have been reported, however their prevalence and clinical manifestations are not well known. Untreated TARTs may lead to testicular structural damage and infertility. This study was conducted to investigate the prevalence of TARTs in male patients with CAH, and characterize the manifestations to identify contributing factors to TART.
Methods: Among 102 CAH patients aged 0–30 years, 24 male patients have been regularly followed up in our outpatient clinic at Severance Children’s Hospital from January 2000 to December 2014. In order to reveiw the characteristics of TART patients, we calculated the mean levels of hormones during the 5 years before the time of investigation. Five patients underwent follow-up scrotal ultrasonography (US) after adjusting the dosage of glucocorticoids.
Results: TARTs were detected in 8 of the 13 patients (61.5%). The median age of TARTs diagnosis was 20.2 years with the youngest case being 15.5 years old. The mean serum level of adrenocorticotropic hormone (ACTH) was higher in the TARTs patient group compared to the non-TARTs group (P<0.05). The tumor size decreased in 3 cases, slightly increased in 1 case, and had no change in another case.
Conclusion: The serum ACTH level might be associated with the growth promoting factor for TARTs, but the exact mechanism has not been clearly identified. Screening for TARTs using US is important in male patients with CAH for early-detection and prevention of ongoing complications, such as infertility.
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Avila NA / 1996 / Testicular adrenal rest tissue in congenital adrenal hyperplasia: findings at Gray-scale and color Doppler US / Radiology 198 : 99 ~ 104
Avila NA / 1999 / Testicular adrenal rest tissue in congenital adrenal hyperplasia: comparison of MR imaging and sonographic findings / AJR Am J Roentgenol 172 : 1003 ~ 1006
Aycan Z / 2013 / Prevalence and long-term follow-up outcomes of testicular adrenal rest tumours in children and adolescent males with congenital adrenal hyperplasia / Clin E
Barwick TD / 2005 / Embryology of the adrenal glands and its relevance to diagnostic imaging / Clin Radiol 60 : 953 ~ 959
Cabrera MS / 2001 / Long term outcome in adult males with classic congenital adrenal hyperplasia / J Clin Endocrinol Metab 86 : 3070 ~ 3078
Avila NA / 1999 / Testicular adrenal rest tissue in congenital adrenal hyperplasia: comparison of MR imaging and sonographic findings / AJR Am J Roentgenol 172 : 1003 ~ 1006
Aycan Z / 2013 / Prevalence and long-term follow-up outcomes of testicular adrenal rest tumours in children and adolescent males with congenital adrenal hyperplasia / Clin E
Barwick TD / 2005 / Embryology of the adrenal glands and its relevance to diagnostic imaging / Clin Radiol 60 : 953 ~ 959
Cabrera MS / 2001 / Long term outcome in adult males with classic congenital adrenal hyperplasia / J Clin Endocrinol Metab 86 : 3070 ~ 3078
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Untreated Congenital Adrenal Hyperplasia with 17-α Hydroxylase/17,20-Lyase Deficiency Presenting as Massive Adrenocortical Tumor
Endocrinology and Metabolism
2015 .01
-
Epidemiology and Long-Term Adverse Outcomes in Korean Patients with Congenital Adrenal Hyperplasia: A Nationwide Study
Endocrinology and Metabolism
2022 .02
-
Long-Term Outcomes of Congenital Adrenal Hyperplasia
Endocrinology and Metabolism
2022 .08
-
Clinical and molecular review of atypical congenital adrenal hyperplasia
Annals of Pediatirc Endocrinology & Metabolism
2015 .01
-
Adrenal Morphology as an Indicator of Long-Term Disease Control in Adults with Classic 21-Hydroxylase Deficiency
Endocrinology and Metabolism
2022 .02
-
Successful pregnancy and delivery of a patient with congenital adrenal hyperplasia
Obstetrics & Gynecology Science
2016 .01
-
Compound heterozygosity for a whole gene deletion and p.R124C mutation in CYP21A2 causing nonclassic congenital adrenal hyperplasia
Annals of Pediatirc Endocrinology & Metabolism
2018 .01
-
Lipoid Congenital Adrenal Hyperplasia Diagnosed in an Infant with Hyperpigmentation Only by Targeted Exome Sequencing
Journal of mucopolysaccharidosis and rare disease
2017 .01
-
Repetitive ultrasonographic assessment of adrenal size and shape changes: a clue for an asymptomatic sex hormone-secreting adenoma
Journal of Veterinary Science
2017 .03
-
Details in adrenal surgery
대한외과학회 학술대회 초록집
2016 .11
-
Laparoscopic Retroperitoneoscopic Removal of an Adrenal Hemangioma: a Case Report
The Journal of Endocrine Surgery
2021 .09
-
Testicular microlithiasis in a boy with X-linked adrenal hypoplasia congenita
Annals of Pediatirc Endocrinology & Metabolism
2018 .01
-
Prevalence of Adrenal Insufficiency in Korean Patients undergoing Total Knee Arthroplasty
Annals of geriatric medicine and research
2024 .03
-
Embryonic Development and Adult Regeneration of the Adrenal Gland
Endocrinology and Metabolism
2020 .01
-
Recent advances in biochemical and molecular analysis of congenital adrenal hyperplasia due to 21-hydroxylase deficiency
Annals of Pediatirc Endocrinology & Metabolism
2016 .01
-
Clinicopathological Features of Adrenal Tumors: a Ten-year Study in Yazd, Iran
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Adrenal Schwannoma: Rare Entity of Adrenal Incidentaloma
The Journal of Endocrine Surgery
2016 .01
-
Case Reports of Congenital Adrenal Hyperplasia with Ambiguous Genitalia: Different Final Gender Results
대한외과학회 학술대회 초록집
2018 .11
-
부신피질기능저하증에 대한 한의학적 치험 1례
대한한방내과학회지
2017 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0