지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
오류제보하기
Elevated blood pressure (BP) is the leading modifiable risk factor for stroke and the benefit of BPlowering therapy on the stroke risk reduction is well established. The optimal BP target forpreventing stroke and other vascular events have been controversial, but the evidences fromepidemiological studies and randomized controlled trials (RCTs) support intensive BP lowering forgreater vascular protection, particularly for stroke prevention. For secondary stroke prevention, theevidence of intensive BP lowering benefit is limited since only a single RCT for patients withlacunar infarctions was conducted and most data were driven by exploratory analyses. In acuteintracerebral hemorrhage, immediate BP lowering targeting systolic BP<140 mm Hg isrecommended by guidelines based on the results from RCTs. In contrast, in acute ischemic stroke,early BP lowering is not usually recommended because of no benefit on functional outcome andfuture vascular events and potential harm of stroke progression. This review aims to summarizethe updated evidence for optimal BP management for primary and secondary stroke preventionand in patients with acute stroke.
목차
등록된 정보가 없습니다.
참고문헌 (83)
참고문헌 신청
WHO / 2013 / A global brief on hypertension / World Health Organization
O’Donnell MJ / 2016 / Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE):a case-control study / Lancet 388:761~775
Lewington S / 2002 / Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies / Lancet 360:1903~1913
Lawes CM / 2003 / Blood pressure and cardiovascular disease in the Asia Pacific region / J Hypertens 21:707~716
MacMahon S / 1990 / Blood pressure, stroke, and coronary heart disease. Part 1, prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias / Lancet 335:765~774
O’Donnell MJ / 2016 / Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE):a case-control study / Lancet 388:761~775
Lewington S / 2002 / Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies / Lancet 360:1903~1913
Lawes CM / 2003 / Blood pressure and cardiovascular disease in the Asia Pacific region / J Hypertens 21:707~716
MacMahon S / 1990 / Blood pressure, stroke, and coronary heart disease. Part 1, prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias / Lancet 335:765~774
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