지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아내분비학회 Annals of Pediatirc Endocrinology & Metabolism Annals of Pediatirc Endocrinology & Metabolism 제23권 제4호
- 발행연도
- 2018.1
- 수록면
- 196 - 203 (8page)
이용수
초록· 키워드
오류제보하기
Purpose: The hemoglobin glycation index (HGI) represents the degree of nonenzymatic glycation and has been positively associated with cardiometabolic risk factors (CMRFs) and cardiovascular disease in adults. This study aimed to investigate the association between HGI, components of metabolic syndrome (MS), and alanine aminotransferase (ALT) in a pediatric nondiabetic population. Methods: Data from 3,885 subjects aged 10–18 years from the Korea National Health and Nutrition Examination Survey (2011–2016) were included. HGI was defined as subtraction of predicted glycated hemoglobin (HbA1c) from measured HbA1c. Participants were divided into 3 groups according to HGI tertile. Components of MS (abdominal obesity, fasting glucose, triglycerides, high-density lipoprotein cholesterol, and blood pressure), and proportion of MS, CMRF clustering (≥2 of MS components), and elevated ALT were compared among the groups. Results: Body mass index (BMI) z-score, obesity, total cholesterol, ALT, abdominal obesity, elevated triglycerides, and CMRF clustering showed increasing HGI trends from lower-to-higher tertiles. Multiple logistic regression analysis showed the upper HGI tertile was associated with elevated triglycerides (odds ratio, 1.65; 95% confidence interval, 1.18–2.30). Multiple linear regression analysis showed HGI level was significantly associated with BMI z-score, HbA1c, triglycerides, and ALT. When stratified by sex, age group, and BMI category, overweight/obese subjects showed linear HGI trends for presence of CMRF clustering and ALT elevation. Conclusion: HGI was associated with CMRFs in a Korean pediatric population. High HGI might be an independent risk factor for CMRF clustering and ALT elevation in overweight/obese youth. Further studies are required to establish the clinical relevance of HGI for cardiometabolic health in youth.
목차
등록된 정보가 없습니다.
참고문헌 (34)
참고문헌 신청
Ng M / 2014 / Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013 / Lancet 384:766~781
Fazeli Farsani S / 2013 / Global trends in the incidence and prevalence of type 2 diabetes in children and adolescents:a systematic review and evaluation of methodological approaches / Diabetologia 56:1471~1488
Nam HK / 2017 / Trends in the prevalence of extreme obesity among Korean children and adolescents from 2001 to 2014. / J Pediatr Endocrinol Metab 30:517~523
이정현 / 2015 / Incidence trends and associated factors of diabetes mellitus in Korean children and adolescents: a retrospective cohort study in Busan and Gyeongnam / Annals of Pediatirc Endocrinology & Metabolism 20(4):206~212
Styne DM / 2017 / Pediatric obesity-assessment, treatment, and prevention: an endocrine society clinical practice guideline / J Clin Endocrinol Metab 102:709~757
Fazeli Farsani S / 2013 / Global trends in the incidence and prevalence of type 2 diabetes in children and adolescents:a systematic review and evaluation of methodological approaches / Diabetologia 56:1471~1488
Nam HK / 2017 / Trends in the prevalence of extreme obesity among Korean children and adolescents from 2001 to 2014. / J Pediatr Endocrinol Metab 30:517~523
이정현 / 2015 / Incidence trends and associated factors of diabetes mellitus in Korean children and adolescents: a retrospective cohort study in Busan and Gyeongnam / Annals of Pediatirc Endocrinology & Metabolism 20(4):206~212
Styne DM / 2017 / Pediatric obesity-assessment, treatment, and prevention: an endocrine society clinical practice guideline / J Clin Endocrinol Metab 102:709~757
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Consistency of the Glycation Gap with the Hemoglobin Glycation Index Derived from a Continuous Glucose Monitoring System
Endocrinology and Metabolism
2020 .01
-
Relationships between Thigh and Waist Circumference, Hemoglobin Glycation Index, and Carotid Plaque in Patients with Type 2 Diabetes
Endocrinology and Metabolism
2020 .01
-
Cardiometabolic risk factors and metabolic syndrome based on severity of obesity in Korean children and adolescents: data from the Korea National Health and Nutrition Examination Survey 2007–2018
Annals of Pediatirc Endocrinology & Metabolism
2022 .12
-
Waist- to-Height Ratio as an Index for Cardiometabolic Risk in Adolescents: Results from the 1998−2008 KNHANES
Yonsei Medical Journal
2016 .01
-
Dynamic Cardiac Magnetic Resonance Fingerprinting During Vasoactive Breathing Maneuvers: First Results
Journal of Cardiovascular Imaging
2023 .04
-
Association of Types of Meal Skipping with Cardio-metabolic Risk Factors in Korean Adults: The 7th Korea National Health and Nutrition Examination Survey (2016–2018)
Korean Journal of Family Medicine
2024 .09
-
근접치료용 방사성 동위원소의 선량분포 확인을 위한 디지털 반도체 센서의 제작 및 평가
의학물리
2015 .12
-
Serum alanine aminotransferase levels are closely associated with metabolic disturbances in apparently healthy young adolescents independent of obesity
Clinical and Experimental Pediatrics
2019 .01
-
Association between metabolically healthy obesity and carotid intima-media thickness in Korean adolescents with overweight and obesity
Annals of Pediatirc Endocrinology & Metabolism
2024 .08
-
Elevated Alanine Aminotransferase in Early Pregnancy and Subsequent Development of Gestational Diabetes and Preeclampsia
Journal of Korean Medical Science
2020 .01
-
Association between Abdominal Obesity and Cardiovascular Risk Factors in Adults with Normal Body Mass Index: Based on the Sixth Korea National Health and Nutrition Examination Survey
Journal of Obesity & Metabolic Syndrome
2019 .01
-
Prevalence of hyperuricemia and its association with metabolic syndrome and cardiometabolic risk factors in Korean children and adolescents: analysis based on the 2016-2017 Korea National Health and Nutrition Examination Survey
Clinical and Experimental Pediatrics
2019 .01
-
Factors associated with Obesity among Korean Adolescents based on the Seventh Korea National Health and Nutrition Examination Survey (2016)
Child Health Nursing Research
2019 .01
-
Hemoglobin Camperdown [β104Arg→Ser] Detection During Hemoglobin A1c Measurement via Capillary Electrophoresis
Annals of Laboratory Medicine
2016 .01
-
Association between Elevated Alanine Aminotransferase and Urosepsis in Children with Acute Pyelonephritis
Pediatric Gastroenterology, Hepatology & Nutrition
2016 .01
-
Correlation of Cardiovascular Risk Factors with Central Obesity and Multiple Body Mass Index in Korea
Korean Journal of Family Medicine
2017 .01
-
Glycemic Control Is Associated with Histological Findings of Nonalcoholic Fatty Liver Disease
Diabetes and Metabolism Journal
2024 .05
-
Long working hours and overweight and obesity in working adults
대한직업환경의학회지
2016 .08
-
Relationship between hs-CRP and HbA1c in Diabetes Mellitus Patients: 2015-2017 Korean National Health and Nutrition Examination Survey
전남의대학술지
2021 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0