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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Introduction
The basic concept of recanalization treatmentof acute ischemic stroke is early removal ofthrombi occluding the cerebral vessels beforethe ischemic brain tissue injured irreversibly.The mission can be achieved by mechanicaland/or pharmacologic methods. Figurativelyspeaking, it is a battle with thrombi. To win thebattle we need to know about the thrombuswhich is composed largely of platelet aggregatesand fibrin networks. Traditionally fibrinolyticshave been applied as the primary pharmaceuti-cals, which are not always successful regardlessof the delivery methods. Theoretically approach-ing both aspects, fibrinolysis and antiplateletaction, will be more efficient because they maypotentiate the clot lysis. This paper will brieflyreview a relatively recent antiplatelet drug,platelet glycoprotein (GP) IIb/IIIa receptor antag-onist which can be used in that purpose togeth-er with fibrinolytics. For the convenience, theaction of platelets in the formation of thrombuswill be reviewed shortly first.
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