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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 120 - 127 (8page)
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초록· 키워드
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Background: Yeoncheon is an endemic region for hemorrhagic fever with renal syndrome (HFRS) and has been reporting HFRS cases intermittently in other seasons, including autumn. This study was conducted to determine whether a seasonal variation pattern of HFRS exists in Yeoncheon. Materials and Methods: From 2002 to 2016, raw data of the number of patients with HFRS in Yeoncheon and nationwide was collected from the Korea Center for Disease Control and Prevention. On the basis of the raw data, the incidence per 100,000 population was calculated for each month of the year. The twelve months were divided into four quarters, and the proportion of the disease by each quarter was calculated. The effects of sex, age, quarter, and time on HFRS occurrence were analyzed by Poisson regression analysis. Results: A total of 6,132 HFRS cases occurred nationwide, and 62 cases occurred in Yeoncheon. The incidence of the disease in Yeoncheon (9.07/100,000) was statistically higher than that nationwide (0.81/100,000). The quarterly incidence showed that occurrence proportion of HFRS was high in the third and fourth quarters (12.9%, 67.5%) nationwide, whereas it was relatively similar in all quarters in Yeoncheon (17.7%, 21.0%, 25.8%, 35.5%). The Poisson regression model showed that the relative risk of HFRS nationwide was 1.322 in the third quarter and 6.903 in the fourth quarter, but Yeoncheon had no risk increase by quarter. Conclusion: In this study, HFRS in Yeoncheon demonstrated no seasonal variation pattern compared to that in nationwide Korea, which may be considered a regional characteristic. Furthermore, in other regions where HFRS is endemic, like Yeoncheon, HFRS may arise regardless of seasonal variations.
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참고문헌 (23)
참고문헌 신청
Schmaljohn CS / 1985 / Antigenic and genetic properties of viruses linked to hemorrhagic fever with renal syndrome / Science 227:1041~1044
LeDuc JW / 1987 / Epidemiology of Hantaan and related viruses / Lab Anim Sci 37:413~418
Lee HW / 1989 / Hemorrhagic fever with renal syndrome / Prog Med Virol 36:62~102
Tsai TF / 1987 / Hemorrhagic fever with renal syndrome: mode of transmission to humans / Lab Anim Sci 37:428~430
Lee HW / 1982 / Isolation of Hantaan virus, the etiologic agent of Korean hemorrhagic fever, from wild urban rats / J Infect Dis 146:638~644
LeDuc JW / 1987 / Epidemiology of Hantaan and related viruses / Lab Anim Sci 37:413~418
Lee HW / 1989 / Hemorrhagic fever with renal syndrome / Prog Med Virol 36:62~102
Tsai TF / 1987 / Hemorrhagic fever with renal syndrome: mode of transmission to humans / Lab Anim Sci 37:428~430
Lee HW / 1982 / Isolation of Hantaan virus, the etiologic agent of Korean hemorrhagic fever, from wild urban rats / J Infect Dis 146:638~644
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