지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 95 - 102 (8page)
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초록· 키워드
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The effects of direct hemoperfusion with polymyxin B immobilized fiber (PMX) treatment for septic shock have been recently reported.
However, little evidence of a true benefit on clinical outcomes, including mortality, is available. Herein, we report three cases of intra-abdominal infection associated with refractory septic shock Case 1 was Escherichia coli peritonitis after a colectomy. PMX treatment improved the hemodynamic parameters and lactic acid levels of the patient. In case 2, secondary peritonitis was associated with septic or cardiogenic shock. Septic cardiomyopathy was assumed to be the cause of shock. 24 hours after the use of PMX, cardiac contractility assessed by echocardiography returned to baseline. In case 3, a patient with Burkitt’s lymphoma and neutropenia was found to be gastroenteritis and Klebsiella pneumoniae bacteremia. Intravenous meropenem was administered for 3 days. Hemodynamic parameters improve after the twice use of PMXOverall, the change of serial sequential organ failure assessment score (SOFA) was more significant in surgical cases as compared to the medical case at 72 hours after PMX administration. All patients were discharged from the hospital. In addition to early resuscitation efforts and infection source control, PMX treatment may be beneficial to patients with refractory intra-abdominal infection associated with septic shock.
목차
등록된 정보가 없습니다.
참고문헌 (18)
참고문헌 신청
Cruz DN / 2007 / Effectiveness of polymyxin B-immobilized fiber column in sepsis: a systematic review / Critic Care 11 : R47 ~
Cruz DN / 2009 / Early use of polymyxin B hemoperfusion in abdominal septic shock: the EUPHAS randomized controlled trial / JAMA 301 : 2445 ~ 2452
Hanasawa K / 2000 / A new treatment for endotoxemia with direct hemoperfusion by polymyxin immobilized fiber. 1984 / Ther Apher 4 : 142 ~ 145
Ishizuka M / 2014 / Impact of prothrombin time-International Normalized Ratio on outcome of patients with septic shock receiving polymyxin B cartridge hemoperfusion / Surger
Iwagami M / 2014 / Postoperative polymyxin B hemoperfusion and mortality in patients with abdominal septic shock: a propensity-matched analysis / Crit Care Med 42 : 1187 ~ 11
Cruz DN / 2009 / Early use of polymyxin B hemoperfusion in abdominal septic shock: the EUPHAS randomized controlled trial / JAMA 301 : 2445 ~ 2452
Hanasawa K / 2000 / A new treatment for endotoxemia with direct hemoperfusion by polymyxin immobilized fiber. 1984 / Ther Apher 4 : 142 ~ 145
Ishizuka M / 2014 / Impact of prothrombin time-International Normalized Ratio on outcome of patients with septic shock receiving polymyxin B cartridge hemoperfusion / Surger
Iwagami M / 2014 / Postoperative polymyxin B hemoperfusion and mortality in patients with abdominal septic shock: a propensity-matched analysis / Crit Care Med 42 : 1187 ~ 11
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