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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 39 - 46 (8page)
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초록· 키워드
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Background: Dopamine is an inotropic agent that is often selected for continuous infusion. For hemodynamic stability, the rate of infusion is controlled in the range of 5-15 μg/kg/min. This study aimed to compare the time intervals from the administration of dopamine to the onset of its hemodynamic effects when dopamine was administered through three different peripheral veins (the cephalic vein [CV], the great saphenous vein [GSV], and the external jugular vein [EJV]).
Methods: Patients in group 1, group 2, and group 3 received dopamine infusions in the CV, GSV, and EJV, respectively. A noninvasive continuous cardiac output monitor (NICCOMO™, Medis, Ilmenau, Germany) was used to assess cardiac output (CO) and systemic vascular resistance (SVR). Six minutes after intubation, baseline heart rate (HR), systolic blood pressure (BP), diastolic BP, mean arterial pressure (MAP), CO, and SVR values were recorded and dopamine infusion was initiated at a dose of 10 μg/kg/min. Hemodynamic changes at 0, 4, 8, 12, and 15 minutes postinfusion were recorded.
Results: No statistically significant differences were observed among the three groups with respect to the rate of hemodynamic change. In all groups, systolic BP, diastolic BP, MAP, and SVR tended to increase after decreasing for the first 4 minutes; in contrast, HR and CO decreased until 8 minutes, after which they tended to reach a plateau.
Conclusions: For patients under general anesthesia receiving dopamine at 10 μg/kg/min, there were no clinical differences in the effect of dopamine administered through three different peripheral veins.
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참고문헌 (16)
참고문헌 신청
Barak M / 2003 / Hemodynamic and catecholamine response to tracheal intubation: direct laryngoscopy compared with fiberoptic intubation. Cardiovascular and catecholamine res
Brunton L / 1990 / Goodman and Gilman’s The pharmacological basis of therapeutics / McGraw-Hill Companies : 187 ~ 243
Emerman CL / 1988 / Effect of injection site on circulation times during cardiac arrest / Crit Care Med 16 : 1138 ~ 1141
Jarnberg PO / 1981 / .Dopamine infusion in man. Plasma catecholamine levels and pharmacokinetics / Acta Anaesthesiol Scand 25 : 328 ~ 331
Johnson AG. / 1998 / NSAIDs and blood pressure. Clinical importance for older patients / Drugs Aging 12 : 17 ~ 27
Brunton L / 1990 / Goodman and Gilman’s The pharmacological basis of therapeutics / McGraw-Hill Companies : 187 ~ 243
Emerman CL / 1988 / Effect of injection site on circulation times during cardiac arrest / Crit Care Med 16 : 1138 ~ 1141
Jarnberg PO / 1981 / .Dopamine infusion in man. Plasma catecholamine levels and pharmacokinetics / Acta Anaesthesiol Scand 25 : 328 ~ 331
Johnson AG. / 1998 / NSAIDs and blood pressure. Clinical importance for older patients / Drugs Aging 12 : 17 ~ 27
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