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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아알레르기호흡기학회 Allergy Asthma & Respiratory Diseases Allergy Asthma & Respiratory Diseases 제5권 제3호
- 발행연도
- 2017.1
- 수록면
- 141 - 146 (6page)
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초록· 키워드
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Purpose: With increasing use of extracorporeal membrane oxygenation (ECMO) for acute respiratory distress syndrome (ARDS) in children, development of standardized strategies for survival prediction has become crucial; however, this has not been accomplished yet. We evaluated the adult scoring systems for survival prediction used for their applicability in pediatric ARDS and validated them.
Methods: A total of 11 children with ARDS receiving ECMO from 2013 to 2014 were evaluated with adult scoring systems, including the Respiratory Extracorporeal-membrane-oxygenation Survival Prediction (RESP), the PRedicting dEath for SEvere ARDS on VVECMO (PRESERVE), and the ECMOnet scores. We compared the scores on these scales and the clinical characteristics between survivors and nonsurvivors.
Results: Eight of the 11 children died (72.7%). The PRESERVE score (survivors vs. nonsurvivors: 2 vs 5.25, P=0.048), and the ECMOnet score (4.1 vs. 5.63, P=0.048) were lower in survivors than in nonsurvivors. They correctly predicted mortality prediction. There was no significant difference in the RESP score between survivors and non-survivors (-4.33 vs -2.62, P=0.63). The parameters that showed significant differences in this study were peak inspiratory pressure, platelet, and delta neutrophil index. All children who were under immunocompromised conditions, such as those with tumors, or underwent hematopoietic stem cell transplantation died. The immunocompromised status should be considered an important factor for survival prediction in children with ARDS.
Conclusion: This is the first pilot study to apply the survival prediction scoring system to pediatric ARDS with ECMO. It is necessary to establish and modify the survival prediction score system for pediatric ARDS with ECMO.
목차
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참고문헌 (21)
참고문헌 신청
ARDS Definition Task Force / 2012 / Acute respiratory distress syndrome: the Berlin Definition / JAMA 307 : 2526 ~ 2533
Combes A / 2011 / Extracorporeal membrane oxygenation for 2009 influenza A (H1N1)-associated acute respiratory distress syndrome / Semin Respir Crit Care Med 32 : 188 ~ 194
Combes A / 2012 / Extracorporeal membrane oxygenation for respiratory failure in adults / Curr Opin Crit Care 18 : 99 ~ 104
Davidson TA / 1999 / Reduced quality of life in survivors of acute respiratory distress syndrome compared with critically ill control patients / JAMA 281 : 354 ~ 360
Dobyns EL / 1999 / Multicenter randomized controlled trial of the effects of inhaled nitric oxide therapy on gas exchange in children with acute hypoxemic respiratory failur
Combes A / 2011 / Extracorporeal membrane oxygenation for 2009 influenza A (H1N1)-associated acute respiratory distress syndrome / Semin Respir Crit Care Med 32 : 188 ~ 194
Combes A / 2012 / Extracorporeal membrane oxygenation for respiratory failure in adults / Curr Opin Crit Care 18 : 99 ~ 104
Davidson TA / 1999 / Reduced quality of life in survivors of acute respiratory distress syndrome compared with critically ill control patients / JAMA 281 : 354 ~ 360
Dobyns EL / 1999 / Multicenter randomized controlled trial of the effects of inhaled nitric oxide therapy on gas exchange in children with acute hypoxemic respiratory failur
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