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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 534 - 538 (5page)
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초록· 키워드
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We report a case of a 56-year-old woman with breast cancer, ovarian cancer, and diffuse large B-cell lymphoma with a BRCA1 gene mutation. Evidence is mounting that there is a large increase in the risk for hematologic malignancies among patients with genetic changes in the BRCA pathways. The genomic analysis demonstrated a frameshift mutation in the BRCA1 gene: 277_279delinsCC (Phe93fs). It is a novel BRCA1 mutation that has never been reported, and caused malignant lymphoma as well as breast and ovarian cancer.
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등록된 정보가 없습니다.
참고문헌 (15)
참고문헌 신청
Ahn Sei Hyun / 2004 / Prevalence of BRCA1 and BRCA2 Mutations in Korean Breast Cancer Patients / Journal of Korean Medical Science 19 (2) : 269 ~ 274
Chen Y / 2013 / Polymorphisms in DNA repair pathway genes, body mass index, and risk of non-Hodgkin lymphoma / Am J Hematol 88 : 606 ~ 611
Easton DF / 1995 / Breast and ovarian cancer incidence in BRCA1-mutation carriers. Breast Cancer Linkage Consortium / Am J Hum Genet 56 : 265 ~ 271
Friedenson B / 2007 / The BRCA1/2 pathway prevents hematologic cancers in addition to breast and ovarian cancers / BMC Cancer 7 : 152 ~
Han SA / 2011 / The Korean Hereditary Breast Cancer(KOHBRA)study : protocols and interim report / Clin Oncol(R Coll Radiol) 23 : 434 ~ 441
Chen Y / 2013 / Polymorphisms in DNA repair pathway genes, body mass index, and risk of non-Hodgkin lymphoma / Am J Hematol 88 : 606 ~ 611
Easton DF / 1995 / Breast and ovarian cancer incidence in BRCA1-mutation carriers. Breast Cancer Linkage Consortium / Am J Hum Genet 56 : 265 ~ 271
Friedenson B / 2007 / The BRCA1/2 pathway prevents hematologic cancers in addition to breast and ovarian cancers / BMC Cancer 7 : 152 ~
Han SA / 2011 / The Korean Hereditary Breast Cancer(KOHBRA)study : protocols and interim report / Clin Oncol(R Coll Radiol) 23 : 434 ~ 441
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