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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 178 - 184 (7page)
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Purpose The purpose of this study was to evaluate the clinical outcomes of patients treated with radiotherapy (RT) for a carcinoma of the external auditory canal (EAC) and middle ear.
Materials and Methods The records of 32 patients who received RT from 1990 to 2013 were reviewed retrospectively.
The Pittsburgh classification was used to stage all the cancers (early stage, T1/T2 [n=12]; advanced stage, T3/T4 or N positive [n=20]). Twenty-one patients (65.6%) were treated with postoperative RT and 11 patients (34.4%) were treated with definitive RT. The median radiation doses for postoperative and definitive RT were 60 Gy and 64.8 Gy, respectively. Chemotherapy was administered to seven patients (21.9%).
Results The 5-year overall survival and disease-free survival rates for all patients were 57% and 52%, respectively. The disease control rates for the patients with early stage versus advanced stage carcinoma were 55.6% (5/9) and 50% (6/12) in the postoperative RT group and 66.7% (2/3) and 37.5% (3/8) in the definitive RT group, respectively. Overall, 15 cases (14 patients, 46.7%) experienced treatment failure; these failures were classified as local in four cases, regional in one case, and distant in 10 cases. The median follow-up period after RT was 51 months (range, 7 to 286 months).
Conclusion Patients with early stage carcinoma achieved better outcomes when definitive RT was used.
Advanced stage carcinoma patients experienced better outcomes with postoperative RT.
The high rate of distant failure after RT, with or without surgery, reflected the lack of a consensus regarding the best therapeutic approach for treating carcinoma of the EAC and middle ear.
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참고문헌 (23)
참고문헌 신청
Arriaga M / 1990 / Staging proposal for external auditory meatus carcinoma based on preoperative clinical examination and computed tomography findings / Ann Otol Rhinol Lary
Arthur K / 1976 / Radiotherapy in carcinoma of the middle ear and auditory canal / J Laryngol Otol 90 : 753 ~ 762
Boamah H / 2011 / Squamous cell carcinoma of the external auditory canal : a case report / Case Rep Otolaryngol 2011 : 615210 ~
Chang CH / 2009 / Treatments and outcomes of malignant tumors of external auditory canal / Am J Otolaryngol 30 : 44 ~ 48
Chen WY / 2012 / Postoperative intensity-modulated radiotherapy for squamous cell carcinoma of the external auditory canal and middle ear : treatment outcomes, marginal miss
Arthur K / 1976 / Radiotherapy in carcinoma of the middle ear and auditory canal / J Laryngol Otol 90 : 753 ~ 762
Boamah H / 2011 / Squamous cell carcinoma of the external auditory canal : a case report / Case Rep Otolaryngol 2011 : 615210 ~
Chang CH / 2009 / Treatments and outcomes of malignant tumors of external auditory canal / Am J Otolaryngol 30 : 44 ~ 48
Chen WY / 2012 / Postoperative intensity-modulated radiotherapy for squamous cell carcinoma of the external auditory canal and middle ear : treatment outcomes, marginal miss
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