지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.1
- 수록면
- 406 - 413 (8page)
이용수
초록· 키워드
오류제보하기
Background: Community-acquired pneumonia (CAP) is a common respiratory disorder in children, which necessitates hospitalization. Bacterial pneumonia, especially lobar pneumonia and parapneumonic effusions, is associated with considerably severe clinical course and extensive alveolar infiltrates. Serum procalcitonin (PCT) level has been used to distinguish bacterial from viral infections, but its usefulness is disputed. The diagnostic accuracy and usefulness of PCT, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and white blood cell (WBC) count were determined by comparing their values in the patients with CAP with those in healthy controls.
Methods: The serum PCT levels, as well as CRP level, ESR, and WBC counts, were measured in 76 hospitalized patients with CAP (lobar pneumonia, 16; bronchopneumonia, 60) and 18 healthy controls. Serum PCT level was measured using VIDAS BRAHMS PCT (Biomerieux, France), and ROC curve analysis was performed to evaluate its diagnostic accuracy.
Results: Serum PCT levels were higher in the patients with CAP than in healthy controls, especially in the patients with lobar pneumonia than in those with bronchopneumonia. Serum CRP level was also significantly elevated in the patients with CAP, especially in those with lobar pneumonia.
The diagnostic accuracy of serum PCT level for the diagnosis of lobar pneumonia was better than those of serum CRP level and ESR. The serum PCT level was significantly correlated with the CRP level, ESR, and WBC count.
Conclusions: Serum PCT level was a better marker than CRP level or ESR for the diagnosis of lobar pneumonia in children with CAP. (Korean J Lab Med 2010;30:406-13)
목차
등록된 정보가 없습니다.
참고문헌 (26)
참고문헌 신청
Assicot M / 1993 / High serum procalcitonin concentrations in patients with sepsis and infection / Lancet 341 : 515 ~ 518
British Thoracic Society Standards of Care Committee / 2002 / British Thoracic Society Guidelines for the Management of Community Acquired Pneumonia in Childhood / Thorax 57
Christ-Crain M / 2004 / Effect of procalcitonin-guided treatment on antibiotic use and outcome in lower respiratory tract infections: clusterrandomised, single-blinded inter
Courtoy I / 1989 / Accuracy of radiographic differentiation of bacterial from nonbacterial pneumonia / Clin Pediatr 28 : 261 ~ 264
Don M / 2007 / De Candia A, Fasoli L, et al. Efficacy of serum procalcitonin in evaluating severity of community-acquired pneumonia in childhood / Scand J Infect Dis 39 : 12
British Thoracic Society Standards of Care Committee / 2002 / British Thoracic Society Guidelines for the Management of Community Acquired Pneumonia in Childhood / Thorax 57
Christ-Crain M / 2004 / Effect of procalcitonin-guided treatment on antibiotic use and outcome in lower respiratory tract infections: clusterrandomised, single-blinded inter
Courtoy I / 1989 / Accuracy of radiographic differentiation of bacterial from nonbacterial pneumonia / Clin Pediatr 28 : 261 ~ 264
Don M / 2007 / De Candia A, Fasoli L, et al. Efficacy of serum procalcitonin in evaluating severity of community-acquired pneumonia in childhood / Scand J Infect Dis 39 : 12
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