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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 905 - 914 (10page)
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초록· 키워드
오류제보하기
Objective To investigate neural correlates associated with recovery of motor function over 6 months in patients with basal ganglia (BG) stroke using acetazolamide (ACZ) stress brain-perfusion single-photon emission computed tomography (SPECT).Methods Medical records of 22 patients presenting first-ever BG stroke were retrospectively reviewed. Regional cerebral blood flow (CBF) and cerebrovascular reserve (CVR) were measured for 9 regions in each cerebral hemisphere (primary motor cortex, supplementary motor area, premotor cortex, prefrontal cortex, temporal lobe, parietal lobe, occipital lobe, BG, and thalamus). The Fugl-Meyer Assessment (FMA) motor score was used to assess motor function.Results After ACZ injection, CBF of all regions of interest (ROIs) increased compared with baseline. Baseline CBF of all ROIs was not significantly correlated with changes in FMA upper or lower motor score. However, multivariate analysis revealed CVR was significantly associated with change in FMA upper score in the ipsilateral primary motor cortex (R2=0.216, p=0.017), the ipsilateral parietal lobe (R2=0.135, p=0.029), and the contralateral primary motor cortex (R2=0.210, p=0.041).Conclusion CVR in the bilateral primary motor cortex and ipsilateral parietal lobe was associated with restoration of upper motor function 6 months after BG stroke. SPECT is a readily available imaging modality useful in studying brain residual function in patients with BG stroke.
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등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
[학술지(정기간행
Andaluz N / 2010 / Patient selection for revascularization procedures in adult Moyamoya disease based on dynamic perfusion computerized tomography with acetazolamide challen
Calautti C / 2001 / Dynamics of motor network overactivation after striatocapsular stroke: a longitudinal PET study using a fixed-performance paradigm / Stroke 32 : 2534 ~ 25
Carey LM / 2006 / Evolution of brain activation with good and poor motor recovery after stroke / Neurorehabil Neural Repair 20 : 24 ~ 41
Cramer SC / 2007 / Predicting functional gains in a stroke trial / Stroke 38 : 2108 ~ 2114
Andaluz N / 2010 / Patient selection for revascularization procedures in adult Moyamoya disease based on dynamic perfusion computerized tomography with acetazolamide challen
Calautti C / 2001 / Dynamics of motor network overactivation after striatocapsular stroke: a longitudinal PET study using a fixed-performance paradigm / Stroke 32 : 2534 ~ 25
Carey LM / 2006 / Evolution of brain activation with good and poor motor recovery after stroke / Neurorehabil Neural Repair 20 : 24 ~ 41
Cramer SC / 2007 / Predicting functional gains in a stroke trial / Stroke 38 : 2108 ~ 2114
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