지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 625 - 634 (10page)
이용수
초록· 키워드
오류제보하기
Objective To investigate longitudinal changes in language function in left-hemispheric ischemic stroke patients as well as factors that influence language recovery until 1 year after stroke onset. Methods We analyzed data from 235 patients with first-ever left-hemispheric ischemic stroke. All patients completed the Korean version of the Frenchay Aphasia Screening Test (K-FAST) at 7 days (T1), 3 months (T2), 6 months (T3), and 1 year (T4) after stroke onset. Repeated measures analysis of variance (ANOVA) was used to investigate changes in language function between time points. Subgroup analysis was performed according to the K-FAST scores at T1. Stroke lesion volume was assessed using diffusion tensor images, and involvement of language-related brain regions was examined. Multiple regression analysis was used to analyze factors influencing improvement of K-FAST score. Results The K-FAST scores at T1, T2, T3, and T4 differed significantly (p<0.05). In the subgroup analysis, only the severe group showed continuous significant improvement by 1 year. Factors that negatively influenced improvement of language function were the age at onset, initial National Institutes of Health Stroke Scale (NIHSS) score, and initial K-FAST score, whereas education level and stroke lesion volume positively affected recovery. Involvement of language-related brain regions did not significantly influence long-term language recovery after ischemic stroke. Conclusion Recovery of language function varied according to the severity of the initial language deficit. The age at stroke onset, education level, initial severity of aphasia, initial NIHSS score, and total stroke lesion volume were found to be important factors for recovery of language function.
목차
등록된 정보가 없습니다.
참고문헌 (39)
참고문헌 신청
Engelter ST / 2006 / Epidemiology of aphasia attributable to first ischemic stroke : incidence, severity, fluency, etiology, and thrombolysis / Stroke 37:1379~1384
Hoffmann M / 2013 / The spectrum of aphasia subtypes and etiology in subacute stroke / J Stroke Cerebrovasc Dis 22:1385~1392
Andreas Charidimou / 2014 / Why Is It Difficult to Predict Language Impairment and Outcome in Patients with Aphasia after Stroke? / Journal of Clinical Neurology 10(2):75~83
Watila MM / 2015 / Factors predicting poststroke aphasia recovery / J Neurol Sci 352:12~18
Bomi Sul / 2016 / The Prognosis and Recovery of Aphasia Related to Stroke Lesion / Annals of Rehabilitation Medicine 40(5):786~793
Hoffmann M / 2013 / The spectrum of aphasia subtypes and etiology in subacute stroke / J Stroke Cerebrovasc Dis 22:1385~1392
Andreas Charidimou / 2014 / Why Is It Difficult to Predict Language Impairment and Outcome in Patients with Aphasia after Stroke? / Journal of Clinical Neurology 10(2):75~83
Watila MM / 2015 / Factors predicting poststroke aphasia recovery / J Neurol Sci 352:12~18
Bomi Sul / 2016 / The Prognosis and Recovery of Aphasia Related to Stroke Lesion / Annals of Rehabilitation Medicine 40(5):786~793
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