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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한치주과학회 Journal of Periodontal & Implant Science Journal of Periodontal & Implant Science 제41권 제3호
- 발행연도
- 2011.1
- 수록면
- 123 - 130 (8page)
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Purpose: The purpose of this study was to determine the biological effects of cyanoacrylate-combined calcium phosphate (CCP), in particular its potential to act as a physical barrier - functioning like a membrane - in rabbit calvarial defects.
Methods: In each animal, four circular calvarial defects with a diameter of 8 mm were prepared and then filled with either nothing (control group) or one of three different experimental materials. In the experimental conditions, they were filled with CCP alone (CCP group), filled with biphasic calcium phosphate (BCP) and then covered with an absorbable collagen sponge (ACS; BCP/ACS group), or filled with BCP and then covered by CCP (BCP/CCP group).
Results: After 4 and 8 weeks of healing, new bone formation appeared to be lower in the CCP group than in the control group, but the difference was not statistically significant. In both the CCP and BCP/CCP groups, inflammatory cells could be seen after 4 and 8 weeks of healing.
Conclusions: Within the limits of this study, CCP exhibited limited osteoconductivity in rabbit calvarial defects and was histologically associated with the presence of inflammatory cells. However, CCP demonstrated its ability to stabilize graft particles and its potential as an effective defect filler in bone augmentation, if the biocompatibility and osteoconductivity of CCP were improved.
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참고문헌 (28)
참고문헌 신청
김영균 / 200807 / Clinical evaluations of OSTEON? as a new alloplastic material in sinus bone grafting and its effect on bone healing / Journal of Biomedical Materials Research - Part B Applied Biomaterials 86(1):270~277
엄유정 / 2008 / 토끼 두개골에서 새로 개발된 biphasic calcium phosphate의 골형성 효과 : A pilot study / Journal of Periodontal & Implant Science 38(2):163~170
Fleckenstein KB / 2006 / Effect of a hydroxyapatite tricalcium phosphate alloplast on osseous repair in the rat calvarium / J Periodontol 77:39~45
Yun-Young Chang, / 2010 / The Effects of Hydroxyapatite Coated with β-Tricalcium Phosphate in One-Wall Intrabony Defects in Dogs / 생체재료학회지 14(3):111~117
Moreira-Gonzalez A / 2005 / Evaluation of 45S5 bioactive glass combined as a bone substitute in the reconstruction of critical size calvarial defects in rabbits / J Craniofac Surg 16:63~70
엄유정 / 2008 / 토끼 두개골에서 새로 개발된 biphasic calcium phosphate의 골형성 효과 : A pilot study / Journal of Periodontal & Implant Science 38(2):163~170
Fleckenstein KB / 2006 / Effect of a hydroxyapatite tricalcium phosphate alloplast on osseous repair in the rat calvarium / J Periodontol 77:39~45
Yun-Young Chang, / 2010 / The Effects of Hydroxyapatite Coated with β-Tricalcium Phosphate in One-Wall Intrabony Defects in Dogs / 생체재료학회지 14(3):111~117
Moreira-Gonzalez A / 2005 / Evaluation of 45S5 bioactive glass combined as a bone substitute in the reconstruction of critical size calvarial defects in rabbits / J Craniofac Surg 16:63~70
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