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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한치주과학회 Journal of Periodontal & Implant Science Journal of Periodontal & Implant Science 제47권 제6호
- 발행연도
- 2017.1
- 수록면
- 381 - 387 (7page)
이용수
초록· 키워드
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Purpose: The aim of this study was to evaluate volumetric and histologic changes in edentulous alveolar ridge areas after ridge preservation using basic fibroblast growth factor-2 (bFGF-2) in combination with collagenated biphasic calcium phosphate (BCP).
Methods: The experiments were performed in 6 adult male beagle dogs. The following 3 groups were created: 1) ridge preservation with bFGF-2 and collagenated BCP (experimental group), 2) ridge preservation with collagenated BCP (positive control group), and 3) a negative control group in which no ridge preservation procedure was performed. Volumetric change analysis was performed using an optical scanner and casts. Histological observations were made using light microscopy.
Results: After the initial swelling subsided, the magnitude of the volumetric change in the experimental group and positive control group was smaller than in the negative control group. In the experimental group, a distinct trend was observed for the resorption of residual bone and collagen fibers at 4 weeks and for more mature bone and faster healing at 12 weeks.
Conclusions: Based on the findings of the present study, bFGF-2 may be considered for use as a therapeutic molecule in ridge preservation procedures.
목차
등록된 정보가 없습니다.
참고문헌 (18)
참고문헌 신청
Akagawa Y / 2009 / Initial bone regeneration around fenestrated implants in Beagle dogs using basic fibroblast growth factor-gelatin hydrogel complex with varying biodegrada
Araujo MG / 2005 / Dimensional ridge alterations following tooth extraction. An experimental study in the dog / J Clin Periodontol 32 : 212 ~ 218
Fang TD / 2005 / Angiogenesis is required for successful bone induction during distraction osteogenesis / J Bone Miner Res 20 : 1114 ~ 1124
Jung RE / 2008 / Bone morphogenetic protein-2 enhances bone formation when delivered by a synthetic matrix containing hydroxyapatite/tricalciumphosphate / Clin Oral Implants
Jung RE / 2013 / Radiographic evaluation of different techniques for ridge preservation after tooth extraction : a randomized controlled clinical trial / J Clin Periodontol 4
Araujo MG / 2005 / Dimensional ridge alterations following tooth extraction. An experimental study in the dog / J Clin Periodontol 32 : 212 ~ 218
Fang TD / 2005 / Angiogenesis is required for successful bone induction during distraction osteogenesis / J Bone Miner Res 20 : 1114 ~ 1124
Jung RE / 2008 / Bone morphogenetic protein-2 enhances bone formation when delivered by a synthetic matrix containing hydroxyapatite/tricalciumphosphate / Clin Oral Implants
Jung RE / 2013 / Radiographic evaluation of different techniques for ridge preservation after tooth extraction : a randomized controlled clinical trial / J Clin Periodontol 4
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