천식 및 만성 비부비동염을 동반한 환자의 비용에서의 Cytokine 발현

김효열; 하병석; 정승규; 동헌종; 김명순

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자료유형: 학술저널

저자정보: 김효열 하병석 정승규 동헌종 김명순

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제47권 제3호

발행연도: 2004.1

수록면: 227 - 231 (5page)

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Background and Objectives：nes in rhinosinusitis with asthma have not been well understood. We investigated the pattern of cytokine production in chronic sinusitis in asthmatic patients and compare the findings in asthmatic vs. non-asthmatic patients. Materials and Method：We ana-lyzed cytokine levels in nasal polyps from 20 patients with sinusitis & asthma and from 25 patients with sinusitis alone. Evaluated parameters are the levels of the following cytokines：IL-3, IL-4, TGF-β1, IFN-γdisease extent evaluated by degre of polyposis. Results：There was no statistically significant diference between two groups on cytokine levels and preoperative polyposis. Conclusion：This study shows that there was no significant change in cytokine levels of sinusitis acording to the presence of asthma. These findings would suggest the existence of other mechanisms shared by sinusitis and asthma.

#천식·부비동염·사이토카인·기도·비용. #Asthma· Sinusitis· Cytokines· Respiratory tract· Polyps.

참고문헌 (20)

참고문헌 신청

/ 1987 / Regulation of human eosinophil viability, density,and function by granulocyte/macrophage colony-stimulating factor inthe presence of 3T3 fibroblasts. 166 : 129 ~ 14

/ 1990 / IL-4 acts synergistically withIL-1 beta to promote lymphocyte adhesion to microvascular endotheliumby induction of vascular cell adhesion molecule-1 145 : 2886 ~ 28

/ 1990 / Interleukin-4 hasbasophilic and eosinophilic cell growth-promoting activity on cordblood cells 75 : 67 ~ 73

/ 1990 / The cell biology of transforminggrowth factor beta 1032 : 79 ~ 87

/ 1991 / The intranasal ethmoidectomy: An experience with 1, 077procedures 101 : 367 ~ 371

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