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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 219 - 225 (7page)
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초록· 키워드
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This study was investigated the synergistic effects from the combination of cefalexin and gentamicin (CCG) against Staphylococcus spp. isolated from bovine milk. Minimum inhibitory concentrations (MICs) and fractional inhibitory concentration (FIC) index were determined for 16 bacteria from 13 bovine farms in Gyeongsangnam province by the National Committee for Clinical Laboratory Standards broth microdilution procedure. Antimicrobial agents tested included cefalexin, gentamicin and CCG.
Against Staphylococcus spp. tested, the MIC ranges of cefalexin, gentamicin and CCG were 0.25∼1.0, 0.5∼0.125 and 0.06∼0.125 g/mL, respectively. In addition, the FIC index ranges of CCG against most of the isolates was 0.28∼0.43 and the FIC index of CCG against 2 strains of Staphylococcus haemolyticus (S. haemolyticus) was 0.59. In conclusion, CCG has a high antibacterial activity against Staphylococcus isolates, then the combination may be applied for the treatment of bovine mastitis caused by Staphylococcus spp.
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참고문헌 (28)
참고문헌 신청
Rajala-Schultz PJ / 2009 / Antimicrobial resistance and genotypic characterization of coagulase-negative staphylococci over the dry period / Vet Microbiol 134:55~64
Rysanek D / 2009 / Monitoring major mastitis pathogens at the population level based on examination of bulk tank milk samples / J Dairy Res 76:117~123
Taponen S / 2016 / Species distribution and in vitro antimicrobial susceptibility of coagulase-negative staphylococci isolated from bovine mastitic milk / Acta Vet Scand 58:12
Thomas V / 2015 / Antimicrobial susceptibility monitoring of mastitis pathogens isolated from acute cases of clinical mastitis in dairy cows across Europe: VetPath results / Int J Antimicrob Agents 46:13~20
Unal N / 2012 / Panton-Valentine leukocidin and some exotoxins of Staphylococcus aureus and antimicrobial susceptibility profiles of staphylococci isolated from milks of small ruminants / Trop Anim Health Prod 44:573~579
Rysanek D / 2009 / Monitoring major mastitis pathogens at the population level based on examination of bulk tank milk samples / J Dairy Res 76:117~123
Taponen S / 2016 / Species distribution and in vitro antimicrobial susceptibility of coagulase-negative staphylococci isolated from bovine mastitic milk / Acta Vet Scand 58:12
Thomas V / 2015 / Antimicrobial susceptibility monitoring of mastitis pathogens isolated from acute cases of clinical mastitis in dairy cows across Europe: VetPath results / Int J Antimicrob Agents 46:13~20
Unal N / 2012 / Panton-Valentine leukocidin and some exotoxins of Staphylococcus aureus and antimicrobial susceptibility profiles of staphylococci isolated from milks of small ruminants / Trop Anim Health Prod 44:573~579
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