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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 203 - 208 (6page)
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This study investigated the effect of Jerusalem artichoke (Helianthus tuberosus L.) extract on Blood Glucose and Lipid Metabolism in Streptozotocin (70 mg/kg B.W., i.p.)-induced Diabetic Rats. Sprague-Dawley male rats (200∼220 g) were divided into normal control group (NC), diabetic control group (DC) and Jerusalem artichoke treated diabetic group (DJ). Diabetes was induced by single intraperitoneal injection of streptozotocin as a dose of 70 mg/kg body weight. Food (p＜0.001) and water (p＜0.05) intakes were higher in diabetic groups than the normal group. Body weight gain and food efficiency ratio were significantly lower in diabetic groups than normal group (p＜0.01). However, they were higher in the DJ group than in the DC group. The serum levels of AST and ALT were significantly lower in the DJ group than in the DC group (p＜0.05). The serum level of HDL-C was significantly higher in the DJ group than in the DC group (p＜0.001). The serum levels of Triglyceride (p＜0.05), LDL-C (p＜0.001), and glucose (p＜0.001) were significantly lower in the DJ group than in the DC group. At 3 and 4 weeks after the experiment, blood glucose level in the DJ group was significantly lower than the DC group (p＜0.05). In conclusion, these results indicated that Jerusalem artichoke can prevent or retard the development of diabetic complications via its beneficial effects for alleviating the hyperglycemia and improved lipid metabolism.
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등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Arbeeny CA / 1992 / Inhibition of fatty acid synthesis decrease very-low density lipoprotein secretion in the hamster / J Lipid Res 33 : 843 ~ 851
Bach V / 2012 / Effects of harvest time and variety on sensory quality and chemical composition of Jerusalem artichoke (Helianthus tuberosus) tubers / J Food Chem 133 : 82 ~
Baltacioglu C / 2012 / Chips production from Jerusalem artichoke (Helianthus tuberosus L) / Food Nutr Sci 3 : 1321 ~ 1328
Bursch W / 1986 / Cytoprotective effect of the prostacyclin derivative iloprost against liver cell death induced by the hepatotoxins carbon tetracholoride and brombenzen / Kl
Connelly K / 2007 / Clinically relevant models of diabetic cardiac complications / Circ Res 101 (6) : 78 ~ 80
Bach V / 2012 / Effects of harvest time and variety on sensory quality and chemical composition of Jerusalem artichoke (Helianthus tuberosus) tubers / J Food Chem 133 : 82 ~
Baltacioglu C / 2012 / Chips production from Jerusalem artichoke (Helianthus tuberosus L) / Food Nutr Sci 3 : 1321 ~ 1328
Bursch W / 1986 / Cytoprotective effect of the prostacyclin derivative iloprost against liver cell death induced by the hepatotoxins carbon tetracholoride and brombenzen / Kl
Connelly K / 2007 / Clinically relevant models of diabetic cardiac complications / Circ Res 101 (6) : 78 ~ 80
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