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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 249 - 259 (11page)
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초록· 키워드
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Background/Aims: Although the detrimental effects of several dietary components on the promotion of non-alcoholic fatty liver disease are well known, no studies have assessed the role of dietary vitamin B6. Moreover, studies on the associations between dietary components or body composition indices and liver steatosis assessed by transient elastography are rare. Our aim was to identify the nutritional factors and anthropometric parameters associated with liver steatosis.
Methods: In this cross-sectional study, we enrolled 168 individuals (35% obese) who underwent a liver steatosis assessment by Controlled Attenuation Parameter measurement and nutritional assessment.
Results: Tertiles of vitamin B6 intake were positively associated with hepatic steatosis (B=1.89, P=0.026, confidence interval [CI] 0.03-0.80) as well as with triglycerides, glucose, alanine aminotransferase (ALT), and body mass index . In obese individuals, after multivariable analysis, the Controlled Attenuation Parameter score was still associated with triglycerides, ALT, and total protein intake (B=0.56, P=0.01, CI 0.10-1.02). Participants in tertile I (low intake) had a lower Controlled Attenuation Parameter than those in tertile III (P=0.01).
Conclusions: We found a positive association between hepatic steatosis or Controlled Attenuation Parameter score and vitamin B6/total protein intake, probably related to the high intake of meat. Vitamin B6 might have a pathogenic role related to the increase of hepatic steatosis.
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참고문헌 (22)
참고문헌 신청
An BK / 1995 / Effects of dietary vitamin B~ 6 levels on lipid concentration and fatty acid composition in growing chicks / Asian-Australasian Journal of Animal Sciences 8 :
Arturo Pujia / 2016 / Individuals with Metabolically Healthy Overweight/Obesity Have Higher Fat Utilization than Metabolically Unhealthy Individuals / Nutrients 8 (12) : 2 ~
Bedogni G / 2005 / Prevalence of and risk factors for nonalcoholic fatty liver disease:the Dionysos nutrition and liver study / Hepatology 42 : 44 ~ 52
Centers for Disease Control and Prevention / 2006 / Tobacco use among adults ? United States, 2005 / MMWR : 1145 ~ 1148
Cunnane SC / 1984 / Accumulation of linoleic and gamma-linolenic acids in tissue lipids of pyridoxine-deficient rats / J Nutr 114 : 1754 ~ 1761
Arturo Pujia / 2016 / Individuals with Metabolically Healthy Overweight/Obesity Have Higher Fat Utilization than Metabolically Unhealthy Individuals / Nutrients 8 (12) : 2 ~
Bedogni G / 2005 / Prevalence of and risk factors for nonalcoholic fatty liver disease:the Dionysos nutrition and liver study / Hepatology 42 : 44 ~ 52
Centers for Disease Control and Prevention / 2006 / Tobacco use among adults ? United States, 2005 / MMWR : 1145 ~ 1148
Cunnane SC / 1984 / Accumulation of linoleic and gamma-linolenic acids in tissue lipids of pyridoxine-deficient rats / J Nutr 114 : 1754 ~ 1761
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