지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 51 - 57 (7page)
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초록· 키워드
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Purpose: To compare the clinical efficacy of anticholinergics for managing diabetes mellitus-associated overactive bladder (DM OAB) versus idiopathic overactive bladder (OAB) in Korean women. Methods: We conducted a multicenter, prospective, parallel-group, open-label, 12-week study. Women (20–65 years old) with OAB symptoms for over 3 months were assigned to the DM OAB and idiopathic OAB groups. Changes in the Overactive Bladder Symptom Score (OABSS), urgency, urinary urgency incontinence, nocturia, daytime frequency according to a voiding diary, uroflowmetry, and postvoid residual urine volume (PVR) at the first visit (V1), week 4 (V2), and week 12 (V3) were compared. Results: No significant difference was found between the baseline patient characteristics of the DM OAB and idiopathic OAB groups. Treatment with solifenacin was associated with improvements in urgency, urinary urgency incontinence, nocturia, frequency according to a voiding diary, and the total OABSS between V1 and V2 and between V1 and V3. Moreover, a significant improvement in urgency and urge incontinence was found between V2 and V3 in the DM OAB group. However, no significant changes were found in any other parameters. There were no significant differences between the DM OAB group and the idiopathic OAB group except for urgency and urge incontinence at V2 (3.71 vs. 2.28 and 0.47 vs. 0.32, respectively). Conclusions: The patients who received solifenacin demonstrated improved urgency, urinary urgency incontinence, nocturia, frequency according to a voiding diary, and total OABSS. Management with solifenacin was equally effective for both DM-related OAB and idiopathic OAB.
목차
등록된 정보가 없습니다.
참고문헌 (34)
참고문헌 신청
Yalla SV / 1995 / Correlation of American Urological Association symptom index with obstructive and nonobstructive prostatism / J Urol 153(3 Pt 1):674~679
Jackson S / 1997 / The patient with an overactive bladder: symptoms and quality-of-life issues / Urology 50(6A Suppl):18~22
Milsom I / 2001 / How widespread are the symptoms of an overactive bladder and how are they managed? A population-based prevalence study / BJU Int 87:760~766
Brown JS / 1996 / Urinary incontinence in older women: who is at risk? Study of Osteoporotic Fractures Research Group / Obstet Gynecol 87(5 Pt 1):715~721
Kim JC / 2000 / Changes of detrusor contractility and growth factors in streptozotocin-induced / Korean J Urol 41:615~621
Jackson S / 1997 / The patient with an overactive bladder: symptoms and quality-of-life issues / Urology 50(6A Suppl):18~22
Milsom I / 2001 / How widespread are the symptoms of an overactive bladder and how are they managed? A population-based prevalence study / BJU Int 87:760~766
Brown JS / 1996 / Urinary incontinence in older women: who is at risk? Study of Osteoporotic Fractures Research Group / Obstet Gynecol 87(5 Pt 1):715~721
Kim JC / 2000 / Changes of detrusor contractility and growth factors in streptozotocin-induced / Korean J Urol 41:615~621
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