지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 1,128 - 1,133 (6page)
이용수
초록· 키워드
오류제보하기
Purpose: The purpose of this study was to determine the effect-site concentration (Ce) of remifentanil in 50% of patients (EC50) and 95% of patients (EC95) for smooth laryngeal mask airway (LMA) removal in adults under propofol and remifentanil anesthesia. Materials and Methods: Twenty-five patients of ASA physical status I‒II and ages 18‒60 years who were to undergo minor gynecological or orthopedic surgery were assessed in this study. Anesthesia was induced and maintained with propofol and remifentanil target-controlled infusion (TCI). Remifentanil was maintainedat a predetermined Ce during the emergence period. The modified Dixon’s up-and-down method was used to determine the remifentanil concentration, starting from 1.0 ng/mL (step size of 0.2 ng/mL). Successful removal of the LMA was regardedas absence of coughing/gagging, clenched teeth, gross purposeful movements,breath holding, laryngospasm, or desaturation to SpO2<90%. Results: The mean±SD Ce of remifentanil for smooth LMA removal after propofol anesthesia was 0.83±0.16 ng/mL. Using isotonic regression with a bootstrapping approach, the estimated EC50 and EC95 of remifentanil Ce were 0.91 ng/mL [95% confidence interval(CI), 0.77‒1.07 ng/mL] and 1.35 ng/mL (95% CI, 1.16‒1.38 ng/mL), respectively.
Conclusion: Our results showed that remifentanil TCI at an established Ce is a reliable technique for achieving safe and smooth emergence without coughing, laryngospasm,or other airway reflexes.
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Abdi W / 2010 / Sparing the larynx during gynecological laparoscopy: a randomized trial comparing the LMA Supreme and the ETT / Acta Anaesthesiol Scand 54 : 141 ~ 146
Aouad MT / 2009 / The effect of low-dose remifentanil on responses to the endotracheal tube during emergence from general anesthesia / Anesth Analg 108 : 1157 ~ 1160
Arain SR / 2005 / Desflurane enhances reactivity during the use of the laryngeal mask airway / Anesthesiology 103 : 495 ~ 499
Baird MB / 1999 / Removal of the laryngeal mask airway : factors affecting the incidence of post-operative adverse respiratory events in 300 patients / Eur J Anaesthesiol 16
Batra YK / 2005 / The efficacy of a subhypnotic dose of propofol in preventing laryngospasm following tonsillectomy and adenoidectomy in children / Paediatr Anaesth 15 : 109
Aouad MT / 2009 / The effect of low-dose remifentanil on responses to the endotracheal tube during emergence from general anesthesia / Anesth Analg 108 : 1157 ~ 1160
Arain SR / 2005 / Desflurane enhances reactivity during the use of the laryngeal mask airway / Anesthesiology 103 : 495 ~ 499
Baird MB / 1999 / Removal of the laryngeal mask airway : factors affecting the incidence of post-operative adverse respiratory events in 300 patients / Eur J Anaesthesiol 16
Batra YK / 2005 / The efficacy of a subhypnotic dose of propofol in preventing laryngospasm following tonsillectomy and adenoidectomy in children / Paediatr Anaesth 15 : 109
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