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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 1,454 - 1,460 (7page)
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초록· 키워드
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Purpose: There have been few studies on gender difference in the impact of a urine albumin-to-creatinine ratio (UACR) within the normal range on the risk of hypertension. We evaluated whether the association between the UACR below the microalbuminuria range and the incident risk of hypertension is different between men and women.
Materials and Methods: A total of 1173 individuals (442 men and 731 women) aged 40 to 70 years without hypertension was examinedat baseline (2005–2008) and followed (2008–2011). We defined the UACR as the amount of albumin (mg/dL) divided by creatinine (g/dL) in randomly voided urine. The subjects were classified according to UACR tertile.
Results: During an average of 2.6 years of follow-up, 57 men (12.9%) and 66 women (9.0%) developed hypertension. In multivariable-adjusted models, the odds ratio for new-onset hypertension comparing the highest and lowest tertiles of UACR was 1.83 [95% confidence interval (CI) 0.85–3.94] in men and 2.69 (95% CI 1.27–5.73) in women. In stratified analyses by menopausal status,higher tertiles of UACR were associated with an increased risk of incident hypertension in postmenopausal women.
Conclusion: Higher normal UACR levels were associated with an increased risk of incident hypertension in women. The UACR could have a clinical role in predicting the development of hypertension.
목차
등록된 정보가 없습니다.
참고문헌 (36)
참고문헌 신청
Lewington S / 2002 / Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies / Lancet 360:1903~1913
Lopez AD / 2006 / Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data / Lancet 367:1747~1757
Blood Pressure Lowering Treatment Trialists’ Collaboration / 2008 / Effects of different regimens to lower blood pressure on major cardiovascular events in older and younger adults: meta-analysis of randomised trials / BMJ 336:1121~1123
D’Agostino RB Sr / 2008 / General cardiovascular risk profile for use in primary care: the Framingham Heart Study / Circulation 117:743~753
Klag MJ / 1996 / Blood pressure and end-stage renal disease in men / N Engl J Med 334:13~18
Lopez AD / 2006 / Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data / Lancet 367:1747~1757
Blood Pressure Lowering Treatment Trialists’ Collaboration / 2008 / Effects of different regimens to lower blood pressure on major cardiovascular events in older and younger adults: meta-analysis of randomised trials / BMJ 336:1121~1123
D’Agostino RB Sr / 2008 / General cardiovascular risk profile for use in primary care: the Framingham Heart Study / Circulation 117:743~753
Klag MJ / 1996 / Blood pressure and end-stage renal disease in men / N Engl J Med 334:13~18
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