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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 72 - 79 (8page)
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초록· 키워드
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Purpose: This study sought to determine the 1-year clinical effectiveness and safety of a biodegradable, polymer-containing BiolimusA9TM-eluting stent (BES) in Korean patients with acute coronary syndrome (ACS). Materials and Methods: A total of 1000 ACS patients with 1251 lesions who underwent implantation of BESs at 22 centers in Koreawere enrolled between May 2011 and July 2013. We assessed major adverse cardiac events (MACE) defined as the composite of cardiac death, non-fatal myocardial infarction (MI), and clinical-driven target vessel revascularization at 12 months. Results: Patient mean age was 62.6±11.4 years. 72.8% of the patients were male, 28.5% had diabetes, 32.8% had multi-vessel disease (MVD), and 47.9% presented with acute MI (AMI). The mean global registry of acute coronary events risk score of all patients was 103.0±27.6. The number of stents per patient was 1.3±0.6. The incidences of MACE and definite stent thrombosis at 12 months were 3.9% and 0.2%, respectively. On multivariate Cox-regression analysis, age ≥65 years was identified as an independent predictorsof 1-year MACE (hazard ratio=2.474; 95% confidence interval=1.202−5.091). Subgroup analyses revealed no significant differences in the incidence of MACE between patients with and without diabetes (4.3% vs. 3.7%, p=0.667), between those who presented with and without AMI (4.4% vs. 3.4%, p=0.403), and between those with and without MVD (4.6% vs. 3.5%, p=0.387). Conclusion: Our study demonstrated excellent 1-year clinical outcomes of BES implantation in patients at low-risk for ACS.
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등록된 정보가 없습니다.
참고문헌 (2)
참고문헌 신청
Ayman Tantawy / 2017 / Nobori-Biolimus-Eluting Stents versus Resolute Zotarolimus-Eluting Stents in Patients Undergoing Coronary Intervention: A Propensity Score Matching / Yonsei Medical Journal 58(2):290~295
임경섭 / 2013 / Histopathological Comparison among Biolimus, Zotarolimus and Everolimus-Eluting Stents in Porcine Coronary Restenosis Model / Korean Circulation Journal 43(11):744~751
임경섭 / 2013 / Histopathological Comparison among Biolimus, Zotarolimus and Everolimus-Eluting Stents in Porcine Coronary Restenosis Model / Korean Circulation Journal 43(11):744~751
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