지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 170 - 177 (8page)
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Purpose: Preterm infants frequently require red blood cell (RBC) transfusions in neonatal intensive care units (NICU). Storage RBCs undergo many changes during storage periods. We aimed to compare the hemoglobin (Hb) correction effect according to the period of RBC storage and investigate the factors influencing Hb correction. Methods: This retrospective study reviewed the medical records of 289 patients who received RBC transfusion more than once in the NICU of Kosin University Gospel Hospital between February 2006 and March 2016. The subjects were classified into two storage groups: short-term (≤7 days, n=88) and long-term (>7 days, n=201), according to the period of RBC storage. We checked Hb levels by complete blood cell count tests conducted within 2 days before and 5 to 9 days after the first transfusion. We compared the Hb difference between the two groups and analyzed the factors influencing Hb correction. Results: Excluding the use of an invasive ventilator, there was no significant difference between the two groups in terms of clinical characteristics. There was no significant difference in the Hb correction effect between the two groups (P=0.537). Birth weight greater than 1,500 g, higher weight at transfusion, and larger volume of transfusion were significant prognostic factors affecting greater changes in Hb. In addition, surgery experience, higher Hb level at transfusion, and additional blood tests were found to be significantly associated with less changes in Hb. Conclusion: The RBC storage period did not affect the Hb correction effect. The Hb correction effect may be diminished in infants with lower birth weight and lower weight at transfusion under unstable clinical conditions.
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참고문헌 (26)
참고문헌 신청
Quinn K / 2015 / Neonatal transfusion models to determine the impact of using fresh red blood cells on inventory and exposure / Blood Transfus 13:595~599
Lee SH / 1999 / The use of quadruple blood bags transfusion of low birth weight neonates / J Korean Pediatr Soc 42:1122~1129
Bell EF / 2005 / Randomized trial of liberal versus restrictive guidelines for red blood cell transfusion in preterm infants / Pediatrics 115:1685~1691
Kim HM / 1996 / Advances in neonatal care and outcome of low birth weight infants / J Korean Pediatr Soc 39:762~772
김성신 / 2014 / 미숙아에서 최적의 혈색소 / Neonatal medicine 21(2):92~98
Lee SH / 1999 / The use of quadruple blood bags transfusion of low birth weight neonates / J Korean Pediatr Soc 42:1122~1129
Bell EF / 2005 / Randomized trial of liberal versus restrictive guidelines for red blood cell transfusion in preterm infants / Pediatrics 115:1685~1691
Kim HM / 1996 / Advances in neonatal care and outcome of low birth weight infants / J Korean Pediatr Soc 39:762~772
김성신 / 2014 / 미숙아에서 최적의 혈색소 / Neonatal medicine 21(2):92~98
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